Zhao Rong, Zhang Wei-yuan, Zhang Song-wen, Wu Ming-hui, Wang Jian-dong, Xie Zheng, Feng Jing, Pan Jing, Wang Jun-hua, Liu Xin-zhi
Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.
Zhonghua Fu Chan Ke Za Zhi. 2011 Mar;46(3):184-7.
To investigate subtype of HPV infection among women at age of 25 to 54 years in Beijing.
From Sept. 2006 to Dec. 2008, 5552 reproductive women at age of 25 to 54 years classified into each 5-year as group were screened. Each participant completed a questionnaire and a sample of exfoliated cervical cells for liquid-based cytology and HPV subtype gene testing was performed.
The overall prevalence of HPV was 6.68% (371/5552). High-risk HPV and Low-risk HPV prevalence were 5.76% (320/5552) and 2.00% (111/5552), respectively. The most common HPV types were HPV16 (2.61%, 145/5552), HPV58 (0.97%, 54/5552), HPV33 (0.85%, 47/5552), HPV43 (0.74%, 41/5552) and HPV56 (0.70%, 39/5552). There were two peaks of HPV prevalence: groups of 30 - 34 years and 40 - 44 years.
The most common HPV subtypes in Beijing were HPV 16, 58, 33 and 43 and HPV prevalence showed a bi-modal age-specific curve.
调查北京25至54岁女性人乳头瘤病毒（HPV）感染亚型。
2006年9月至2008年12月，对5552名25至54岁的育龄女性进行筛查，每5岁为一组。每位参与者填写一份问卷，并采集宫颈脱落细胞样本进行液基细胞学检查和HPV亚型基因检测。
HPV总体感染率为6.68%（371/5552）。高危型HPV和低危型HPV感染率分别为5.76%（320/5552）和2.00%（111/5552）。最常见的HPV类型为HPV16（2.61%，145/5552）、HPV58（0.97%，54/5552）、HPV33（0.85%，47/5552）、HPV43（0.74%，41/5552）和HPV56（0.70%，39/5552）。HPV感染率有两个高峰：30 - 34岁组和40 - 44岁组。
北京最常见的HPV亚型为HPV 16、58、33和43，且HPV感染率呈现出年龄特异性的双峰曲线。
