Chen Xiangfan, Yan Hong, Cao Yingnan, Li Shiyue, Yang Ningxi, Li Xiaoyan
School of Health Sciences, Wuhan University, Wuhan, Hubei, China.
Beijing Jishuitan Hospital/4th Medical College of Peking University, Beijing, China.
J Int Med Res. 2020 Feb;48(2):300060519889754. doi: 10.1177/0300060519889754.
To investigate human papillomavirus (HPV) infection status and influencing factors among lesbians.
In August to October 2018, 300 lesbians were recruited in Beijing using snowball sampling. Sociodemographic characteristics, behavioural indices and HPV status were measured. Colposcopy was performed on participants with HPV genotypes 16 and 18 and on participants with other high-risk HPV subtypes and positive ThinPrep (TCT) results.
The overall HPV-positive rate was 25%. High number of sexual partners, smoking, drinking, not using condoms and using sex toys during intercourse were identified as HPV infection risk factors. Of the HPV subtypes detected, 84% were high-risk HPV subtypes. The colposcopy results showed that 20 participants (80%) with HPV 16 and HPV 18 had cervical intraepithelial neoplasia I (CIN I) or above lesions. The colposcopy results also showed that 16 participants (64%) infected with other high-risk types of HPV virus and who had positive TCT results had CIN I or above lesions.
The cervical health of lesbians should not be neglected, and appropriate health education should be improved for this group.
调查女同性恋者中人乳头瘤病毒（HPV）感染状况及影响因素。
2018年8月至10月，采用雪球抽样法在北京招募300名女同性恋者。测量其社会人口学特征、行为指标及HPV状况。对HPV 16和18基因型感染者以及其他高危HPV亚型感染者且薄层液基细胞学检测（TCT）结果为阳性者进行阴道镜检查。
HPV总体阳性率为25%。性伴侣数量多、吸烟、饮酒、性交时不使用避孕套以及使用性玩具被确定为HPV感染的危险因素。在检测出的HPV亚型中，84%为高危HPV亚型。阴道镜检查结果显示，20例（80%）HPV 16和HPV 18感染者有宫颈上皮内瘤变I级（CIN I）或以上病变。阴道镜检查结果还显示，16例（64%）感染其他高危型HPV病毒且TCT结果为阳性者有CIN I或以上病变。
女同性恋者的宫颈健康不容忽视，应加强对该群体的适当健康教育。
