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新型隐球菌感染的同时性中枢神经系统并发症。

Simultaneous central nervous system complications of C. neoformans infection.

作者信息

González-Duarte Alejandra, Higera Calleja Jesus, Mitre Vicente Gijón, Ramos Guillermo Garcia

机构信息

Department of Neurology;

出版信息

Neurol Int. 2009 Nov 16;1(1):e22. doi: 10.4081/ni.2009.e22.

DOI:10.4081/ni.2009.e22
PMID:21577360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3093228/
Abstract

The most common neurological manifestation of Cryptococcus neoformans infection is meningitis. Other less common manifestations include parenchymal central nervous system (CNS) granulomatous disease, hydrocephalus and stroke. C. neoformans is often suspected in immunodepressed patients, but it can be easily overlooked in otherwise healthy patients. This paper provides a detailed clinical description of a patient without immunosupression who developed multiple simultaneous neurological manifestations after the infection with C. neoformans.

摘要

新型隐球菌感染最常见的神经学表现是脑膜炎。其他较不常见的表现包括实质性中枢神经系统(CNS)肉芽肿病、脑积水和中风。新型隐球菌感染常被怀疑发生于免疫抑制患者,但在其他方面健康的患者中也很容易被忽视。本文详细描述了一名无免疫抑制的患者,该患者在感染新型隐球菌后同时出现了多种神经学表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f61a/3093228/6d64fa6ae56d/ni-2009-1-e22-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f61a/3093228/85560e6cd3ae/ni-2009-1-e22-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f61a/3093228/6d64fa6ae56d/ni-2009-1-e22-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f61a/3093228/85560e6cd3ae/ni-2009-1-e22-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f61a/3093228/6d64fa6ae56d/ni-2009-1-e22-g002.jpg

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本文引用的文献

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Clin Neurol Neurosurg. 2009 Sep;111(7):638-42. doi: 10.1016/j.clineuro.2009.05.007. Epub 2009 Jun 21.
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[Cryptococcus neoformans meningoencephalitis among apparently immunocompetent patients: description of two cases].[免疫功能正常患者中的新型隐球菌性脑膜脑炎:两例病例描述]
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Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings.
一名艾滋病患者出现隐球菌性脑膜脑炎,伴有严重的局限性神经功能缺损,酷似右侧大脑中动脉大面积梗死。
Cureus. 2021 Apr 30;13(4):e14781. doi: 10.7759/cureus.14781.
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Optical coherence tomography imaging of presumed infection localized to the retina.对疑似局限于视网膜的感染进行光学相干断层扫描成像。
J Curr Ophthalmol. 2019 Feb 6;31(3):353-356. doi: 10.1016/j.joco.2019.01.006. eCollection 2019 Sep.
艾滋病毒感染成人急性隐球菌性脑膜炎的治疗,重点关注资源有限的环境。
Cochrane Database Syst Rev. 2008 Oct 8(4):CD005647. doi: 10.1002/14651858.CD005647.pub2.
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Cerebellar cryptococcoma in an immunocompetent child. Case report.免疫功能正常儿童的小脑隐球菌瘤。病例报告。
J Neurosurg. 2007 Oct;107(4 Suppl):314-7. doi: 10.3171/PED-07/10/314.
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Clin Infect Dis. 2000 Apr;30(4):710-8. doi: 10.1086/313757. Epub 2000 Apr 20.
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[A case of cerebral cryptococcosis, with special reference to computerized tomography findings].
No Shinkei Geka. 1984 May;12(6):725-9.
7
A case of cryptococcal meningoencephalitis and focal cerebral vasculitis with transient immunodeficiency.一例伴有短暂免疫缺陷的新型隐球菌性脑膜脑炎和局灶性脑血管炎。
Acta Neurol (Napoli). 1990 Aug;12(4):301-4.