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（E）-5-氯-3-（2,6-二氯-亚苄基）-吲哚啉-2-酮

(E)-5-Chloro-3-(2,6-dichloro-benzyl-idene)-indolin-2-one.

作者信息

Zhang Hongming, Ankati Haribabu, Akubathini Shashidhar Kumar, Biehl Ed

机构信息

Department of Chemistry, Southern Methodist University, Dallas, TX 75275, USA.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Oct 11;64(Pt 11):o2103. doi: 10.1107/S1600536808031930.

DOI:10.1107/S1600536808031930
PMID:21580967
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2959736/
Abstract

There are two independent mol-ecules of the title compound, C(15)H(8)Cl(3)NO, in the asymmetric unit. Both form inversion dimers via pairs of hydrazide-carbonyl N-H⋯O hydrogen bonds.

摘要

在不对称单元中有两个独立的标题化合物C(15)H(8)Cl(3)NO分子。两者都通过酰肼-羰基N-H⋯O氢键对形成反演二聚体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e04/2959736/32f0228b0190/e-64-o2103-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e04/2959736/a6c63a997f49/e-64-o2103-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e04/2959736/32f0228b0190/e-64-o2103-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e04/2959736/a6c63a997f49/e-64-o2103-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e04/2959736/32f0228b0190/e-64-o2103-fig2.jpg

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3
Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 28;65(Pt 11):o2887. doi: 10.1107/S1600536809043487.
4
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A short history of SHELX.
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4
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