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（7R，8R，8aS）-8-羟基-7-苯基-全氢中氮茚-3-酮

(7R,8R,8aS)-8-Hydr-oxy-7-phenyl-per-hydro-indolizin-3-one.

作者信息

Svorc Lubomír, Vrábel Viktor, Zúžiová Jozefína, Bobošíková Mária, Kožíšek Jozef

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Mar 28;65(Pt 4):o895-6. doi: 10.1107/S160053680901085X.

DOI:10.1107/S160053680901085X
PMID:21582602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2968891/
Abstract

The absolute configuration of the title compound, C(14)H(17)NO(2), was assigned from the synthesis. There are two mol-ecules in the asymmetric unit. Their geometries are very similar and corresponding bond lengths are almost identical [mean deviation for all non-H atoms = 0.015 (2) Å]. The six-membered ring of the indolizine system adopts a chair conformation. In the crystal structure, mol-ecules form chains parallel to the a axis via inter-molecular O-H⋯O hydrogen bonds, which help to stabilize the crystal structure.

摘要

通过合成确定了标题化合物C(14)H(17)NO(2)的绝对构型。不对称单元中有两个分子。它们的几何形状非常相似，相应的键长几乎相同[所有非H原子的平均偏差 = 0.015 (2) Å]。中氮茚系统的六元环呈椅式构象。在晶体结构中，分子通过分子间O-H⋯O氢键形成平行于a轴的链，这有助于稳定晶体结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e4d/2968891/a68af2a16ac7/e-65-0o895-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e4d/2968891/9808edcda5c0/e-65-0o895-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e4d/2968891/a68af2a16ac7/e-65-0o895-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e4d/2968891/9808edcda5c0/e-65-0o895-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e4d/2968891/a68af2a16ac7/e-65-0o895-fig2.jpg

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