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(3aR,8aS,9S,9aR)-9-羟基-全氢-呋喃并[3,2-f]中氮茚-6-酮

(3aR,8aS,9S,9aR)-9-Hydroxy-perhydro-furo[3,2-f]indolizin-6-one.

作者信息

Svorc Lubomír, Vrábel Viktor, Zúžiová Jozefína, Marchalín Stefan, Kožíšek Jozef

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 1;65(Pt 8):o1731-2. doi: 10.1107/S1600536809024283.

DOI:10.1107/S1600536809024283
PMID:21583447
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2977186/
Abstract

In the title compound, C(10)H(15)NO(3), the central six-membered ring of the indolizine system adopts a chair conformation, while the oxopyrrolidine and hydro-furan rings attached to the indolizine ring system have envelope conformations. In the crystal, the mol-ecules form chains parallel to the b axis via inter-molecular O-H⋯O hydrogen bonds. The absolute configuration was assigned from the synthesis.

摘要

在标题化合物C(10)H(15)NO(3)中，中氮茚系统的中心六元环呈椅式构象，而连接在中氮茚环系统上的氧代吡咯烷环和氢呋喃环呈信封式构象。在晶体中，分子通过分子间O-H⋯O氢键形成平行于b轴的链。绝对构型由合成确定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56dd/2977186/f48cf1a63f26/e-65-o1731-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56dd/2977186/af945fc44ba9/e-65-o1731-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56dd/2977186/f48cf1a63f26/e-65-o1731-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56dd/2977186/af945fc44ba9/e-65-o1731-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56dd/2977186/f48cf1a63f26/e-65-o1731-fig2.jpg

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