Teh Chin Hoe, Teoh Siew Chin, Yeap Chin Sing, Chan Kit Lam, Fun Hoong-Kun
Acta Crystallogr Sect E Struct Rep Online. 2009 Mar 28;65(Pt 4):o898-9. doi: 10.1107/S1600536809010502.
The title quassinoid compound, C(20)H(24)O(9)·CH(3)OH·2H(2)O, is a natural eurycomanone isolated from the roots of Eurycoma longifolia. The mol-ecules contain a fused five-ring system, with one tetra-hydro-furan ring adopting an envelope conformation, one tetra-hydro-pyran-2-one ring in a screw boat conformation, one cyclo-hexenone ring in a half-chair conformation and two cyclo-hexane rings in chair conformations. Intra-molecular C-H⋯O inter-actions generate S(5) ring motifs and an O-H⋯O inter-action generates an S(7) ring motif. In the crystal, mol-ecules are linked via inter-molecular O-H⋯O inter-actions along the b axis and further stacked along a axis. The absolute configuration of the title compound was inferred from previously solved structures of its analogues.
标题喹啉类化合物C(20)H(24)O(9)·CH(3)OH·2H(2)O是从长叶刺蒺藜根中分离得到的一种天然刺蒺藜素。分子包含一个稠合的五环体系，其中一个四氢呋喃环呈信封构象，一个四氢吡喃-2-酮环呈螺旋船构象，一个环己烯酮环呈半椅构象，两个环己烷环呈椅构象。分子内C-H⋯O相互作用产生S(5)环模式，O-H⋯O相互作用产生S(7)环模式。在晶体中，分子通过分子间O-H⋯O相互作用沿b轴相连，并沿a轴进一步堆积。标题化合物的绝对构型是根据其类似物先前解析的结构推断出来的。
