Department of Maternal-Fetal Medicine, ICGON, Hospital Clinic-IDIBAPS, University of Barcelona and Centre for Biomedical Research on Rare Diseases (CIBER-ER), Barcelona, Spain.
Ultrasound Obstet Gynecol. 2011 Jul;38(1):57-61. doi: 10.1002/uog.8974. Epub 2011 Jun 20.
To evaluate the reproducibility of estimation of power Doppler-derived fractional moving blood volume (FMBV) in the uterine cervix of women with uncomplicated pregnancies.
Two experienced operators evaluated 30 uncomplicated singleton pregnancies at 20-24 weeks of gestation. The PDU box was positioned in a mid-sagittal view of the cervix, including the internal os and external os, in the same plane as that in which cervical length is measured. Two consecutive examinations were performed by each operator, in each of which the cervical length was measured and five consecutive good-quality images with PDU information were obtained. The region of interest (ROI) (cervix) was delineated offline and FMBV, which expresses the percentage of blood occupying the ROI, was calculated with purpose-designed software. Intra- and interobserver intraclass correlation coefficients (ICCs) and mean differences with 95% limits of agreement (LOA) were calculated.
The median gestational age at examination was 22 + 0 weeks. Measurements (median ± SD) obtained for cervical length and FMBV were as follows: Operator A: 37 ± 7.4 mm and 8.11 ± 2.9%; Operator B: 37.5 ± 9.3 mm and 7.9 ± 3.3%, respectively. The intra- and interobserver ICCs for FMBV were 0.88 (95% CI, 0.75-0.94) and 0.82 (95% CI, 0.64-0.94), respectively. There was a mean difference in FMBV measurement between operators of - 0.2 ± 1.75% (95% LOA, - 3.7 to 3.2%).
Reproducible assessment of cervical blood perfusion through estimation of FMBV can be achieved while cervical length is being measured.
评估在无并发症妊娠的女性宫颈中使用彩色能量多普勒（power Doppler）技术评估分数运动血流容积（FMBV）的可重复性。
两名有经验的操作者在 20-24 孕周对 30 例无并发症的单胎妊娠进行评估。PDU 盒被放置在宫颈的正中矢状面，包括宫颈内口和宫颈外口，与测量宫颈长度的同一平面。每位操作者进行两次连续检查，每次检查均测量宫颈长度，并获得 5 个连续的具有 PDU 信息的良好质量图像。离线描绘感兴趣区（ROI）（宫颈），并用专门设计的软件计算 FMBV，FMBV 表示血液占据 ROI 的百分比。计算了观察者内和观察者间的组内相关系数（ICC）和平均差异及其 95%一致性界限（LOA）。
检查时的中位孕龄为 22+0 周。获得的宫颈长度和 FMBV 测量值（中位数±标准差）如下：操作者 A：37±7.4mm 和 8.11±2.9%；操作者 B：37.5±9.3mm 和 7.9±3.3%。FMBV 的观察者内和观察者间 ICC 分别为 0.88（95%可信区间，0.75-0.94）和 0.82（95%可信区间，0.64-0.94）。操作者之间 FMBV 测量值的平均差异为-0.2±1.75%（95%LOA，-3.7 至 3.2%）。
在测量宫颈长度的同时，可以实现对宫颈血流灌注的可重复评估，通过估计 FMBV。
