Department of Neurology, Faculty of Medicine, Maltepe University, Istanbul, Turkey.
Indian J Ophthalmol. 2011 May-Jun;59(3):229-30. doi: 10.4103/0301-4738.81038.
The Charles Bonnet Syndrome (CBS) is typically characterized by visual hallucinations in elderly people without cognitive defects. This article presents the case of an 80-year-old male patient with a one-year history of visual hallucinations, secondary to glaucoma, in both eyes. Neither a dopamine agonist nor cholinesterase inhibitor therapy improved his symptoms. In this case, the hallucinations were gradually improved after administration of a GABAergic drug, pregabalin, for diabetic polyneuropathy. Placebo-controlled clinical trials would be needed to support this effect of pregabalin, as suggested by this association.
查尔斯·邦纳综合征（CBS）通常以无认知缺陷的老年人群中出现视觉幻觉为特征。本文介绍了一例 80 岁男性患者的病例，该患者双眼患有青光眼，有一年的视觉幻觉病史。多巴胺激动剂和胆碱酯酶抑制剂治疗均未改善其症状。在这种情况下，由于糖尿病性多发性神经病，给予 GABA 能药物普瑞巴林后，幻觉逐渐改善。需要安慰剂对照临床试验来支持普瑞巴林的这种作用，正如这种关联所表明的那样。
