Fox 因子争夺 T 细胞静止。
Fox factors fight over T cell quiescence.
机构信息
Center for Immunology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
出版信息
Nat Immunol. 2011 Jun;12(6):522-4. doi: 10.1038/ni.2040.
DOI:10.1038/ni.2040
PMID:21587312
Abstract
The transcription factor Foxp1 helps maintain the quiescence of naive T cells by inhibiting IL-7Rα expression and diminishing signaling by the kinase Erk.
摘要
转录因子 Foxp1 通过抑制 IL-7Rα 的表达和减少激酶 Erk 的信号转导，帮助维持初始 T 细胞的静止状态。
Zotero 插件