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蛛网膜下腔穿刺后头痛的骶管生理盐水注射治疗。

Caudal normal saline injections for the treatment of post-dural puncture headache.

机构信息

Department of Anaesthesiology and Intensive Care Medicine Klinikum Bernburg, Teaching Hospital, Martin Luther University Halle-Wittenberg, Bernburg, Germany.

出版信息

Pain Physician. 2011 May-Jun;14(3):271-9.

Abstract

BACKGROUND

Post-dural puncture headache (PDPH) is the most common complication of procedures in which the dura mater is penetrated.

OBJECTIVES

To evaluate the effectiveness of caudal saline injections as a therapeutic approach for handling post-dural puncture headache.

STUDY DESIGN

Prospective observational study between 1995 and 2010.

SETTING

Associated teaching hospital.

METHODS

A 5-cm 20-gauge short-beveled needle, connected by extension tube to a 20-mL syringe filled with normal saline was used for injection. During injection in increments (limited by patient discomfort), the patients were asked continually to quantify their pain experience on a visual analog scale (VAS) and on a 0-3 verbal categorical rating scale (VRS) after 50, 80 and 100 mL of infusion over a 20 minute period.

LIMITATIONS

This study is limited by its sample size, observational design, and lack of long-term outcomes.

RESULTS

PDPH occurred in 60 of 1,716 patients undergoing dural puncture (3.5%). It was significantly more common in women and occurred more often in young adults. The rate was highest in the spinal catheter group (13%) and lowest in the Sprotte needle group (0.98%). Fifty-six patients underwent caudal saline injections which were repeated in sessions of 1-2 times a day for 1-2 days. Most patients (n = 48) needed 3 or 4 (n=18) sessions. Mean volumes during the 4 sessions were 120.0 mL, 114.9 mL, 106.5 mL, and 97.8 mL. Four patients were finally treated with a blood patch.

CONCLUSIONS

The use of fine gauge pencil-point needles may reduce the incidence of PDPH. The technique of repeated caudal saline injections is easy, rapid, and effective in providing the patient with almost immediate headache relief. In cases where this treatment fails, a blood patch should be considered. Observations from this study suggest that randomized, controlled, double-blind studies may be warranted.

摘要

背景

硬脊膜穿破后头痛(PDPH)是硬脊膜被穿透的过程中最常见的并发症。

目的

评估骶管盐水注射作为处理硬脊膜穿破后头痛的治疗方法的有效性。

研究设计

1995 年至 2010 年期间进行的前瞻性观察研究。

地点

附属教学医院。

方法

使用 5cm 20 号短斜面针,通过延长管与装满生理盐水的 20ml 注射器相连进行注射。在递增注射(受患者不适限制)过程中,患者在 20 分钟内连续通过视觉模拟评分(VAS)和 0-3 级口头分类评分(VRS)来评估他们的疼痛体验,在输注 50、80 和 100ml 后。

局限性

本研究受到样本量、观察设计和缺乏长期结果的限制。

结果

在 1716 例硬脊膜穿刺患者中,有 60 例(3.5%)发生 PDPH。女性发生率明显更高,且在年轻成年人中更常见。脊髓导管组发生率最高(13%),Sprotte 针组发生率最低(0.98%)。56 例患者接受骶管盐水注射,每天重复 1-2 次,持续 1-2 天。大多数患者(n=48)需要 3 或 4 次(n=18)治疗。4 次治疗的平均体积分别为 120.0ml、114.9ml、106.5ml 和 97.8ml。4 例患者最终接受了血贴治疗。

结论

使用细针铅笔点针可能会降低 PDPH 的发生率。重复骶管盐水注射技术简单、快速,能迅速为患者提供头痛缓解。如果这种治疗失败,应考虑血贴。本研究的观察结果表明,可能需要进行随机、对照、双盲研究。

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