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一种使用大容量血液填充法预防鞘内导管泵更换后硬膜穿刺后头痛的新方法。

A new approach using high volume blood patch for prevention of post-dural puncture headache following intrathecal catheter pump exchange.

作者信息

Abdulla Susanne, Vielhaber Stefan, Heinze Hans-Jochen, Abdulla Walied

机构信息

Department of Neurology, Otto-von-Guericke University, Magdeburg, Germany ; Department of Neurology, Medizinische Hochschule Hannover, Hannover, Germany ; German Center for Neurodegenerative Diseases, Magdeburg, Germany.

Department of Neurology, Otto-von-Guericke University, Magdeburg, Germany ; German Center for Neurodegenerative Diseases, Magdeburg, Germany.

出版信息

Int J Crit Illn Inj Sci. 2015 Apr-Jun;5(2):93-8. doi: 10.4103/2229-5151.158395.

Abstract

BACKGROUND

In an observational study, complications of intrathecal catheter pumps necessitating surgical exchange were analyzed. Also the use of a high-volume prophylactic epidural blood patch (EBP) during surgery for preventing post-dural puncture headache (PDPH) with a follow-up for 1 year is described.

MATERIALS AND METHODS

In 22 patients with refractory chronic pain of cancer/noncancer origin or severe spasticity, who were receiving intrathecal morphine including adjuvants or baclofen for symptom relief, catheter exchange with or without pump was performed. In patients with documented symptoms of PDPH following initial intrathecal catheter implantation, a prophylactic EBP with a high blood volume was used for PDPH prevention during surgery. Catheters were replaced using 40 mL EBP before entering dural space at a speed of 5mL/min into the epidural space. Patients were asked to quantify pain experience and functional ability.

RESULTS

From a sample of 72 patients admitted for catheter exchange with or without pump, 22 patients (33%) (12 male, 10 female) had a history of PDPH following initial implantation. Diagnostic and therapeutic measures occurring with malfunction of intrathecal catheter pump systems were described. Twenty-one patients were successfully treated with prophylactic EBP, while one patient could not be properly evaluated because of intracranial bleeding as the underlying disease.

CONCLUSIONS

A new approach using a high-volume prophylactic EBP for preventing PDPH following catheter exchange is presented. The efficacy and safety of this technique for 1 year follow-up have been evaluated and was found to be safe and potentially effective.

摘要

背景

在一项观察性研究中,对需要手术更换的鞘内导管泵并发症进行了分析。此外,还描述了在手术期间使用大容量预防性硬膜外血贴(EBP)预防硬膜穿刺后头痛(PDPH)并进行了1年随访的情况。

材料与方法

对22例患有癌症/非癌症来源的难治性慢性疼痛或严重痉挛的患者进行了研究,这些患者正在接受鞘内吗啡(包括佐剂)或巴氯芬以缓解症状,进行了有或无泵的导管更换。对于初次鞘内导管植入后有PDPH症状记录的患者,在手术期间使用大容量预防性EBP预防PDPH。在进入硬膜外间隙之前,以5mL/分钟的速度使用40mL EBP更换导管进入硬膜外间隙。要求患者对疼痛体验和功能能力进行量化。

结果

在72例因有或无泵而接受导管更换的患者样本中,22例患者(33%)(12例男性,10例女性)在初次植入后有PDPH病史。描述了鞘内导管泵系统故障时发生的诊断和治疗措施。21例患者成功接受了预防性EBP治疗,而1例患者因潜在疾病颅内出血而无法得到妥善评估。

结论

提出了一种使用大容量预防性EBP预防导管更换后PDPH的新方法。对该技术1年随访的有效性和安全性进行了评估,发现其安全且可能有效。

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