Vieira A
Applied Sciences, Nutrition Research Laboratory, Kin-9600, Simon Fraser University, Burnaby, BC, V5A 1S6 Canada.
Pharmacognosy Res. 2010 Sep;2(5):293-5. doi: 10.4103/0974-8490.72326.
In relation to pharmacognosy, an objective of many ethnobotanical studies is to identify plant species to be further investigated, for example, tested in disease models related to the ethnomedicinal application. To further warrant such testing, research evidence for medicinal applications of these plants (or of their major phytochemical constituents and metabolic derivatives) is typically analyzed in biomedical databases.
As a model of this process, the current report presents novel information regarding traditional anti-inflammation and anti-infection medicinal plant use. This information was obtained from an interview-based ethnobotanical study; and was compared with current biomedical evidence using the Medline(®) database.
Of the 8 anti-infection plant species identified in the ethnobotanical study, 7 have related activities reported in the database; and of the 6 anti-inflammation plants, 4 have related activities in the database.
Based on novel and complimentary results from the ethnobotanical and biomedical database analyses, it is suggested that some of these plants warrant additional investigation of potential anti-inflammatory or anti-infection activities in related disease models, and also additional studies in other population groups.
在生药学领域，许多民族植物学研究的一个目标是识别有待进一步研究的植物物种，例如，在与民族医学应用相关的疾病模型中进行测试。为了进一步确保此类测试的合理性，通常会在生物医学数据库中分析这些植物（或其主要植物化学成分和代谢衍生物）药用应用的研究证据。
作为这一过程的模型，本报告展示了有关传统抗炎和抗感染药用植物使用的新信息。这些信息来自一项基于访谈的民族植物学研究，并使用Medline(®)数据库与当前的生物医学证据进行了比较。
在民族植物学研究中确定的8种抗感染植物物种中，数据库中报告了7种具有相关活性；在6种抗炎植物中，有4种在数据库中有相关活性。
基于民族植物学和生物医学数据库分析的新的补充结果，建议对其中一些植物在相关疾病模型中潜在的抗炎或抗感染活性进行进一步研究，并在其他人群中开展更多研究。
