基于 DNA 切割依赖的石墨烯猝灭 DNA zyme 的无标记荧光检测 Cu(II)离子。
Label-free fluorescent detection of Cu(II) ions based on DNA cleavage-dependent graphene-quenched DNAzymes.
机构信息
Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education, China), School of Environmental Science and Technology, Dalian University of Technology, Dalian, 116024, China.
出版信息
Chem Commun (Camb). 2011 Jul 21;47(27):7749-51. doi: 10.1039/c1cc12006a. Epub 2011 May 18.
PMID:21589990
Abstract
We developed a novel and general methodology to design a label-free fluorescent Cu(II) sensor based on internal DNA cleavage and an extrinsic fluorophore in a graphene/DNAzymes complex with high sensitivity and selectivity.
摘要
我们开发了一种新颖且通用的方法，用于设计基于内部分子切割和外源性荧光团的无标记荧光 Cu(II)传感器，该传感器具有高灵敏度和选择性，基于石墨烯/DNA 酶复合物。
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