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输尿管镜下球囊扩张输尿管口碎石术后是否需要留置输尿管支架管?一项多中心随机对照研究。

Is ureteral stenting really necessary after ureteroscopic lithotripsy with balloon dilatation of ureteral orifice? A multi-institutional randomized controlled study.

机构信息

ESOGU Medical Faculty Urology Department, Meselik, Eskişehir, Turkey.

出版信息

World J Urol. 2011 Dec;29(6):731-6. doi: 10.1007/s00345-011-0697-9. Epub 2011 May 18.

Abstract

PURPOSE

Our aim was to evaluate the role of balloon dilatation of the ureteral orifice on the decision to stent after ureteroscopy.

MATERIALS AND METHODS

We prospectively enrolled 505 patients from two clinics, undergoing ureteroscopy (URS) for urolithiasis. Patients having balloon dilatation of the ureteral orifice and uncomplicated ureteroscopy were randomized to be either stented (n = 144) or nonstented (n = 142). Ureteroscopy was done with a 9.8 rigid ureteroscope. For dilatation of ureteral orifice, 18Fr-4 cm balloons were used (Uromax™, Boston Scientific, USA). Holmium laser or pneumatic devices were used for lithotripsy. In the second postoperative week, patients were asked to assess: pain, dysuria, and urgency using a 10-cm visual analog score (VAS) and unplanned visits. In each visit, urinalysis, urine culture, plain X-ray, and ultrasound examinations were performed. Six months after URS, follow-up IVU was performed to evaluate ureteral narrowing. Results for the separate clinics were not revealed until the end of study.

RESULTS

There were no significant differences between the two groups regarding gender, age, preoperative serum creatinine levels, stone size, stone side and location, lithotripsy type, pain, infectious complications, unplanned visits, and ureteral narrowing. However, irritative symptoms were more common in the stented group. Success rates of 97.8 and 97.2% were similar in the unstented and stented groups.

CONCLUSION

In uncomplicated URS, balloon dilatation of the ureteral orifice should not significantly affect the decision for or against stent placement. Avoiding stents lowers costs and gives fewer irritative symptoms.

摘要

目的

我们旨在评估输尿管口球囊扩张在输尿管镜检查后支架置入决策中的作用。

材料与方法

我们前瞻性地纳入了来自两个诊所的 505 名接受输尿管镜检查(URS)治疗肾结石的患者。接受输尿管口球囊扩张且输尿管镜检查无并发症的患者随机分为支架置入组(n = 144)或非支架置入组(n = 142)。输尿管镜检查采用 9.8 刚性输尿管镜进行。输尿管口扩张采用 18Fr-4cm 球囊(Uromax™,波士顿科学,美国)。钬激光或气压设备用于碎石。术后第 2 周,患者使用 10cm 视觉模拟评分(VAS)评估疼痛、尿痛和尿急,并进行非计划就诊。每次就诊时,均进行尿液分析、尿液培养、平片 X 线和超声检查。URS 后 6 个月,行静脉肾盂造影(IVU)随访以评估输尿管狭窄情况。直到研究结束,才公布两个诊所的结果。

结果

两组在性别、年龄、术前血清肌酐水平、结石大小、结石侧和位置、碎石类型、疼痛、感染并发症、非计划就诊和输尿管狭窄方面无显著差异。然而,支架置入组的刺激性症状更为常见。非支架置入组和支架置入组的成功率分别为 97.8%和 97.2%,相似。

结论

在不复杂的 URS 中,输尿管口球囊扩张不应显著影响支架置入的决策。避免支架置入可降低成本,并减少刺激性症状。

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