Crocetti Andrea, Forti Stella, Del Bo Luca
Fondazione Ascolta e Vivi, Via Foppa 15, Milan, Italy.
Auris Nasus Larynx. 2011 Dec;38(6):735-8. doi: 10.1016/j.anl.2011.02.003. Epub 2011 May 17.
Previous studies report that enhanced power in the delta range (1.5-4Hz) and reduced power in the alpha frequency band (8-12Hz) were most pronounced in the temporal regions. These studies referred to the 8-12Hz activity as tau activity, and they created a new neurofeedback protocol to treat tinnitus using a temporally generated tau rhythm (8-12Hz) and slow waves in the delta range (3-4Hz) for feedback. This study aims to repeat this protocol and to evaluate its effect on tinnitus.
Fifteen normal-hearing patients with tinnitus were treated with the neurofeedback protocol. The Tinnitus Handicap Inventory and Visual Analogue Scales were administered before and after treatment and at 1, 3 and 6 months post-treatment.
After therapy, all questionnaires scores were significant improved, and the improvements persisted throughout the followup period. Moreover, an increasing trend in the tau/delta ratio was observed; specifically, the trend was more stable respect of the pre-recording measure. However, only in some subjects may the signal alone be enough to develop the correct behaviors.
Further studies are necessary to characterize the tinnitus subjects who recovered from and adapted to this psychophysical condition and, therefore, responded to neurofeedback therapy.
先前的研究报告称，δ频段（1.5 - 4Hz）功率增强以及α频段（8 - 12Hz）功率降低在颞区最为明显。这些研究将8 - 12Hz活动称为τ活动，并创建了一种新的神经反馈方案，利用颞区产生的τ节律（8 - 12Hz）和δ频段（3 - 4Hz）的慢波进行反馈来治疗耳鸣。本研究旨在重复该方案并评估其对耳鸣的疗效。
15名耳鸣的听力正常患者接受了神经反馈方案治疗。在治疗前、治疗后以及治疗后1个月、3个月和6个月时进行耳鸣障碍问卷和视觉模拟量表评估。
治疗后，所有问卷得分均显著改善，且这些改善在整个随访期持续存在。此外，观察到τ/δ比值呈上升趋势；具体而言，相对于记录前测量，该趋势更为稳定。然而，只有在一些受试者中，单独的信号可能足以产生正确的行为。
有必要进行进一步研究，以明确从这种心理生理状况中恢复并适应，从而对神经反馈疗法有反应的耳鸣患者的特征。
