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全喉切除术和部分喉切除术后患者与嗓音相关的生活质量

Voice-related quality of life in patients after total and partial laryngectomy.

作者信息

Schindler Antonio, Mozzanica Francesco, Ginocchio Daniela, Invernizzi Arianna, Peri Andrea, Ottaviani Francesco

机构信息

Department of Clinical Sciences "L. Sacco", University of Milan, Milan, Italy.

出版信息

Auris Nasus Larynx. 2012 Feb;39(1):77-83. doi: 10.1016/j.anl.2011.03.009. Epub 2011 May 17.

Abstract

OBJECTIVE

To assess the voice-related quality of life (V-RQOL) in patients after total and partial laryngectomy.

MATERIALS AND METHODS

96 patients treated for laryngeal cancer were enrolled in the study. The cohort of patients was divided into three groups depending on the surgical procedure carried out: total laryngectomy (TL), supracricoid partial laryngectomy (SCL) and/or horizontal glottectomy (HG). The maximum phonation time (MPT) and syllable diadochokinesis, were used for the aerodynamic assessment; Yanagihara score was used for acoustic analysis of the sustained /a/ and the GRBAS scale was used for perceptual assessment. Each of the patients completed the VHI. The Kruskal-Wallis and Mann-Whitney tests were used to analyse the mean difference among the three groups of patients.

RESULTS

A comparison with the values found between groups noted that the TL group showed significantly higher scores of G, R and Yanagihara score, while the HG group showed a significantly higher score of B. No differences were found in the aerodynamic and acoustic measures among the 3 groups. The mean±standard deviations of VHI total score were 35.3±24.5 for TL group, 30.1±21.6 for SCL group, 35.8±9.6 for HG group. No significant difference was found across the three groups.

CONCLUSIONS

V-RQOL seems to be similar in patients who underwent significantly different surgical procedures even if the voice characteristics were different. These findings need to be considered in patient's counselling together with other data on general quality of life after total and partial laryngectomy.

摘要

目的

评估全喉切除术和部分喉切除术后患者的嗓音相关生活质量(V-RQOL)。

材料与方法

96例接受喉癌治疗的患者纳入本研究。根据所实施的手术程序,将患者队列分为三组:全喉切除术(TL)、环状软骨上部分喉切除术(SCL)和/或水平声门切除术(HG)。采用最大发声时间(MPT)和音节重复率进行空气动力学评估;柳原评分用于持续发/a/音的声学分析,GRBAS量表用于感知评估。每位患者均完成嗓音障碍指数(VHI)评估。采用Kruskal-Wallis检验和Mann-Whitney检验分析三组患者之间的平均差异。

结果

组间比较发现,TL组的G、R评分和柳原评分显著更高,而HG组的B评分显著更高。三组在空气动力学和声学指标方面未发现差异。TL组VHI总分的平均值±标准差为35.3±24.5,SCL组为30.1±21.6,HG组为35.8±9.6。三组之间未发现显著差异。

结论

即使嗓音特征不同,接受显著不同手术程序的患者的V-RQOL似乎相似。在对患者进行咨询时,这些发现需要与全喉切除术和部分喉切除术后总体生活质量的其他数据一起考虑。

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