Crosetti Erika, Fantini Marco, Arrigoni Giulia, Salonia Laura, Lombardo Agata, Atzori Alessio, Panetta Valentina, Schindler Antonio, Bertolin Andy, Rizzotto Giuseppe, Succo Giovanni
Head and Neck Service, Candiolo Cancer Institute, FPO IRCCS, Candiolo, Italy.
Otorhinolaryngology Service, Department of Oncology, San Luigi Gonzaga Hospital, University of Turin, Turin, Italy.
Eur Arch Otorhinolaryngol. 2017 Jan;274(1):337-346. doi: 10.1007/s00405-016-4217-9. Epub 2016 Jul 19.
The aim was to investigate telephonic voice intelligibility in patients treated for laryngeal cancer using different approaches. In total, 90 patients treated for laryngeal cancer using different approaches and 12 healthy volunteers were recruited. Each patient and each healthy control read a list of words and sentences during a telephone call. Six auditors listened to each telephonic recording and transcribed the words and sentences they understood. Mean intelligibility rates for each treatment were assessed and compared. Regarding words, the poorest intelligibility was noted for type II open partial horizontal laryngectomies, followed by total laryngectomies. The best intelligibility was found for transoral laser microsurgery, followed by radiotherapy alone. For sentences, the poorest intelligibility was noted for type II open partial horizontal laryngectomies, followed by chemoradiotherapy. The best intelligibility was found for radiotherapy alone and transoral laser microsurgery. More aggressive surgery as well as chemoradiotherapy correlated with significantly poorer outcomes. Transoral laser microsurgery or radiotherapy alone ensured the best telephonic voice intelligibility. Intermediate-advanced T stages at diagnosis also showed significantly poorer intelligibility outcomes, suggesting that T stage represents an independent negative prognostic factor for voice intelligibility after treatment.
目的是研究采用不同方法治疗喉癌的患者的电话语音清晰度。总共招募了90例采用不同方法治疗喉癌的患者和12名健康志愿者。每位患者和每位健康对照在电话中朗读一系列单词和句子。六名听众收听每段电话录音，并转录他们听懂的单词和句子。评估并比较每种治疗方法的平均清晰度率。对于单词，II型开放性部分水平喉切除术的清晰度最差，其次是全喉切除术。经口激光显微手术的清晰度最佳，其次是单纯放疗。对于句子，II型开放性部分水平喉切除术的清晰度最差，其次是放化疗。单纯放疗和经口激光显微手术的清晰度最佳。更激进的手术以及放化疗与明显更差的结果相关。经口激光显微手术或单纯放疗可确保最佳的电话语音清晰度。诊断时处于中晚期T分期的患者的清晰度结果也明显更差，这表明T分期是治疗后语音清晰度的一个独立的负面预后因素。
