Belway D, Tee R, Nathan H J, Rubens F D, Boodhwani M
Department of Perfusion Services, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Perfusion. 2011 Sep;26(5):395-400. doi: 10.1177/0267659111409095. Epub 2011 May 18.
Mild to moderate systemic hypothermia is commonly used as a cerebral protective strategy during adult cardiac surgery. The benefits of this strategy for routine cardiac surgery have been questioned and the adverse effects of hyperthermia demonstrated. The purpose of the present study was to examine current temperature management and monitoring practices during adult cardiac surgery using CPB in Canada.
Web-based survey referring to adult cases undergoing cardiac surgery using CPB without the use of deep hypothermic circulatory arrest. Thirty-two questionnaires were completed, representing a 100% response rate.
The usual management is to cool patients during CPB at 30 (94%) centers for low-risk (isolated primary CABG) cases and at 31 (97%) centers for high-risk (all other) cases. The average nadir temperature at the target site achieved on CPB is 34°C (range 28°C - 36°C). At 26 (81%) centers, patients are typically rewarmed to a target temperature between 36°C and 37°C before separation from CPB. Only 6 (19%) centers reported that thermistors and coupled devices used to monitor blood temperature are checked for accuracy or calibrated according to the product operating directive's schedule or more often.
Contemporary management of adult cardiac surgery under CPB still involves induction of mild to moderate systemic hypothermia. Significant practice variation exists across the country with respect to target temperatures for cooling and rewarming, as well as the site for temperature monitoring. This probably reflects the lack of definitive evidence. There is a need for well-conducted clinical trials to provide more robust evidence regarding temperature management.
轻至中度全身性低温常用于成人心脏手术期间的脑保护策略。该策略对常规心脏手术的益处受到质疑,并且已证实了高温的不良影响。本研究的目的是调查加拿大在使用体外循环(CPB)的成人心脏手术期间当前的体温管理和监测实践。
基于网络的调查,涉及接受CPB心脏手术且未使用深度低温循环停搏的成人病例。共完成了32份问卷,回复率为100%。
通常的管理方式是,在CPB期间,94%的中心对低风险(单纯初次冠状动脉旁路移植术)病例将患者体温降至30℃;97%的中心对高风险(所有其他)病例将患者体温降至31℃。CPB期间目标部位达到的平均最低温度为34℃(范围为28℃至36℃)。在26个(81%)中心中,患者通常在脱离CPB前复温至36℃至37℃的目标温度。只有6个(19%)中心报告,用于监测血液温度的热敏电阻及相关设备会按照产品操作指南的时间表或更频繁地进行准确性检查或校准。
CPB下成人心脏手术的当代管理仍涉及诱导轻至中度全身性低温。在降温及复温的目标温度以及温度监测部位方面,全国存在显著差异实践。这可能反映出缺乏确凿证据。需要开展精心设计的临床试验,以提供关于体温管理的更有力证据。