Uveitis Division, Centro Brasileiro de Ciências Visuais, Belo Horizonte, Brazil.
Ocul Immunol Inflamm. 2011 Jun;19(3):171-9. doi: 10.3109/09273948.2011.581407.
The diagnosis of ocular toxoplasmosis is mainly clinical, based in the presence of focal necrotizing retinochoroiditis often associated with a preexistent chorioretinal scar, and variable involvement of the vitreous, retinal blood vessels, optic nerve, and anterior segment of the eye. Recognition of this clinical spectrum of toxoplasmic retinochoroiditis is crucial, but other infectious, noninfectious, and neoplastic entities should also be considered in the differential diagnosis. Investigations such as serological tests, polymerase chain reaction of ocular fluids, and assessment of intraocular antibody synthesis are helpful in uncertain cases. This article provides an overview of the differential diagnosis of ocular toxoplasmosis, focusing on the most important entities to be considered and emphasizing distinctive features of each one of them in the clinical setting. Ocular toxoplasmosis has multiple clinical manifestations, which partially overlap with those of other entities and these should be carefully considered when making the differential diagnosis, particularly in less typical cases.
眼弓形体病的诊断主要基于临床，依据是存在局灶性坏死性视网膜炎，常伴有先前存在的脉络膜视网膜瘢痕，以及玻璃体液、视网膜血管、视神经和眼前节的不同程度受累。认识到弓形体性视网膜炎的这种临床谱至关重要，但在鉴别诊断中还应考虑其他感染性、非感染性和肿瘤性实体。在不确定的情况下，血清学检查、眼液聚合酶链反应和评估眼内抗体合成等检查有助于诊断。本文概述了眼弓形体病的鉴别诊断，重点关注最需要考虑的重要实体，并强调了它们在临床环境中的各自特征。眼弓形体病有多种临床表现，部分与其他实体重叠，在进行鉴别诊断时应仔细考虑这些表现，特别是在不太典型的情况下。
