Magalhães Ana Carolina, Romanelli Andrea Cardinalli, Rios Daniela, Comar Lívia Picchi, Navarro Ricardo Scarparo, Grizzo Larissa Tercilia, Aranha Ana Cecília Corrêa, Buzalaf Marília Afonso Rabelo
Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil.
Photomed Laser Surg. 2011 Aug;29(8):537-44. doi: 10.1089/pho.2010.2886. Epub 2011 May 19.
This in vitro study aimed to analyze the influence of neodymium-doped yttrium aluminum garnet (Nd:YAG) laser irradiation on the efficacy of titanium tetrafluoride (TiF(4)) and sodium fluoride (NaF) varnishes and solutions to protect enamel against erosion.
The effect of Nd:YAG laser irradiation on NaF and AmF was analyzed; however, there is no available data on the interaction between Nd:YAG laser irradiation and TiF(4).
Bovine enamel specimens were pre-treated with NaF varnish, TiF(4) varnish, NaF solution, TiF(4) solution, placebo varnish, Nd:YAG (84.9 J/cm(2)), Nd:YAG prior to or through NaF varnish, Nd:YAG prior to or through TiF(4) varnish, Nd:YAG prior to or through NaF solution, Nd:YAG prior to or through TiF(4) solution, and Nd:YAG prior to or through placebo varnish. Controls remained untreated. Ten specimens in each group were then subjected to an erosive demineralization (Sprite Zero, 4 × 90 s/day) and remineralization (artificial saliva, between the erosive cycles) cycling for 5 days. Enamel loss was measured profilometrically (μm). Additionally, treated but non-eroded specimens were additionally analyzed by scanning electron microscope (SEM) (each group n = 2). The data were statistically analyzed by ANOVA and Tukey's post-hoc test (p < 0.05).
Only TiF(4) varnish (1.8 ± 0.6 μm), laser prior to TiF(4) varnish (1.7 ± 0.3 μm) and laser prior to TiF(4) solution (1.4 ± 0.3 μm) significantly reduced enamel erosion compared to the control (4.1 ± 0.6 μm). SEM pictures showed that specimens treated with TiF(4) varnish presented a surface coating.
Nd:YAG laser irradiation was not effective against enamel erosion and it did not have any influence on the efficacy of F, except for TiF(4) solution. On the other hand, TiF(4) varnish protected against enamel erosion, without the influence of laser irradiation.
本体外研究旨在分析掺钕钇铝石榴石（Nd:YAG）激光照射对四氟化钛（TiF₄）和氟化钠（NaF）清漆及溶液保护牙釉质免受侵蚀功效的影响。
已分析了Nd:YAG激光照射对NaF和AmF的影响；然而，关于Nd:YAG激光照射与TiF₄之间相互作用的可用数据尚无。
牛牙釉质标本分别用NaF清漆、TiF₄清漆、NaF溶液、TiF₄溶液、安慰剂清漆、Nd:YAG（84.9 J/cm²）、在NaF清漆之前或通过NaF清漆照射的Nd:YAG、在TiF₄清漆之前或通过TiF₄清漆照射的Nd:YAG、在NaF溶液之前或通过NaF溶液照射的Nd:YAG、在TiF₄溶液之前或通过TiF₄溶液照射的Nd:YAG以及在安慰剂清漆之前或通过安慰剂清漆照射的Nd:YAG进行预处理。对照组未作处理。然后每组10个标本进行侵蚀性脱矿（零度雪碧，每天4×90秒）和再矿化（人工唾液，在侵蚀周期之间）循环5天。用轮廓仪测量牙釉质损失（μm）。此外，对经过处理但未侵蚀的标本用扫描电子显微镜（SEM）进行额外分析（每组n = 2）。数据采用方差分析和Tukey事后检验进行统计学分析（p < 0.05）。
与对照组（4.1±0.6μm）相比，只有TiF₄清漆（1.8±0.6μm）、在TiF₄清漆之前照射的激光（1.7±0.3μm）和在TiF₄溶液之前照射的激光（1.4±0.3μm）能显著减少牙釉质侵蚀。SEM图片显示，用TiF₄清漆处理的标本呈现出表面涂层。
Nd:YAG激光照射对牙釉质侵蚀无效，除了TiF₄溶液外，对氟的功效没有任何影响。另一方面，TiF₄清漆可保护牙釉质免受侵蚀，不受激光照射的影响。
