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生物膜与传染病:从生物学到数学,再回归生物学。

Biofilms and infectious diseases: biology to mathematics and back again.

机构信息

Department of Mathematics, Florida State University, Tallahassee, FL 32306, USA.

出版信息

FEMS Microbiol Lett. 2011 Sep;322(1):1-7. doi: 10.1111/j.1574-6968.2011.02314.x. Epub 2011 Jun 16.

Abstract

There has been tremendous growth in biofilm research in the past three decades. This growth has been reflected in development of a wide variety of experimental, clinical, and theoretical techniques fostered by our increased knowledge. Keeping the theoretical developments abreast of the experimental advancements and ensuring that the theoretical results are disseminated to the experimental and clinical community is a major challenge. This manuscript provides an overview of recent developments in each scientific domain. More importantly, this manuscript aims to identify areas where the theory lags behind the experimental understanding (and vice versa). The major themes of the manuscript derive from discussions and presentations at a recent interdisciplinary workshop that brought together a variety of scientists whose underlying studies focus on biofilm processes.

摘要

在过去的三十年中,生物膜研究取得了巨大的发展。这种增长反映在各种实验、临床和理论技术的发展上,这些技术是我们知识增长的结果。保持理论发展与实验进展同步,并确保理论成果传播到实验和临床社区,是一个主要挑战。本文概述了每个科学领域的最新发展。更重要的是,本文旨在确定理论落后于实验理解(反之亦然)的领域。本文的主要主题源自最近一次跨学科研讨会的讨论和演讲,该研讨会汇集了各种科学家,他们的基础研究集中在生物膜过程上。

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