Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, Lyons, NJ 08854, USA.
Gen Hosp Psychiatry. 2011 Mar-Apr;33(2):94-101. doi: 10.1016/j.genhosppsych.2010.12.001. Epub 2011 Jan 19.
Lower use of medication treatment, poorer doctor-patient communication (DPC) and depression stigma are key contributors to mental healthcare disparities among Latinos with depression. The current study investigated the relationship between these key variables and the long-term trajectory of depression in primary care among Latinos.
Participants (N=220) were Latinos presenting to primary care who screened positive for depression. A repeated measures design was used to assess participants at baseline and 6, 25 and 30 months. Repeated measures included depression (Patient Health Questionnaire-9), self-reported quality of DPC and stigma pertaining to antidepressants. Using growth curve modeling, participants' depressive symptom trajectories were examined for a 30-month period. Self-reported utilization of antidepressants, DPC and antidepressant stigma were examined as predictors of the depressive symptom trajectory. In addition, rates of depression improvement/remission and recurrence/relapse were examined.
Improvement/remission was experienced by 69.4% of participants during a 30-month period. Among those who improved/remitted at 6 or 25 months, 63.4% maintained that improvement/remission by 30 months. The long-term trajectory of depressive symptoms demonstrated a significant positive association with antidepressant stigma and significant negative associations with use of antidepressant treatment and quality DPC.
While relapse/recurrence is common, most Latinos in this study experienced improvement in depression over 30 months. For many, there is a considerable time to reach improvement/remission. Also, these findings confirm the significance of antidepressant underutilization, DPC and stigma in the long-term outcome of depression among Latinos in primary care.
药物治疗使用率较低、医患沟通(DPC)较差以及对抑郁症的污名化是导致拉丁裔抑郁症患者心理健康服务差距的主要因素。本研究调查了这些关键变量与拉丁裔人群在初级保健中心的抑郁症长期病程之间的关系。
参与者(N=220)为出现于初级保健中心并经抑郁筛查呈阳性的拉丁裔人群。采用重复测量设计在基线时以及 6、25 和 30 个月时评估参与者。重复测量包括抑郁(患者健康问卷-9)、自我报告的 DPC 质量以及与抗抑郁药相关的污名。使用增长曲线模型,检查了参与者的抑郁症状轨迹,为期 30 个月。自我报告的抗抑郁药使用情况、DPC 和抗抑郁药污名被视为抑郁症状轨迹的预测因素。此外,还检查了抑郁改善/缓解以及复发/复发的发生率。
在 30 个月期间,69.4%的参与者经历了改善/缓解。在 6 或 25 个月时改善/缓解的参与者中,有 63.4%在 30 个月时保持了这种改善/缓解。抑郁症状的长期轨迹与抗抑郁药污名呈显著正相关,与抗抑郁药治疗的使用以及 DPC 质量呈显著负相关。
虽然复发/复发很常见,但本研究中的大多数拉丁裔在 30 个月内经历了抑郁的改善。对于许多人来说,需要相当长的时间才能达到改善/缓解。此外,这些发现证实了在初级保健中心的拉丁裔人群中,抗抑郁药的低使用率、DPC 和污名在抑郁的长期结果中的重要性。