初级保健中小儿哮喘处方模式的变化：处方数据库分析。

Changes in primary care prescribing patterns for paediatric asthma: a prescribing database analysis.

机构信息

Department of Child Health, Division of Applied Health Sciences, University of Aberdeen, Royal Aberdeen Children's Hospital, Westburn Road, Aberdeen AB25 2ZG, UK.

出版信息

Arch Dis Child. 2012 Jun;97(6):521-5. doi: 10.1136/adc.2010.206268. Epub 2011 May 19.

DOI:10.1136/adc.2010.206268

PMID:21596728

Abstract

BACKGROUND

Little is known about the impact of British asthma management guideline revisions. Concerns about the use of high dose inhaled corticosteroids (ICS) in children have resulted in the promotion of add-on therapy.

AIMS

To assess prescribing patterns of asthma medication in children in the primary care setting.

METHODS

Retrospective observational study of asthma prescribing in children aged 0-18 years using primary care database from 2001 to 2006.

RESULTS

The proportion of children prescribed oral corticosteroids increased significantly (from 6% in 2001-2002 to 16% in 2005-2006, p<0.001), while the proportion of children prescribed an ICS dose of >400 mcg decreased from 16.2% to 11.7% (P<0.001). The proportion of children prescribed an add-on therapy and an ICS dose >400 µg, increased from 38.8 % in 2001-2002 to 61.2% in 2005-2006 (p<0.001).

CONCLUSIONS

Although adherence with asthma management guidelines is not optimal, this study has identified improved adherence in primary care.

摘要

背景

目前对于英国哮喘管理指南修订的影响知之甚少。由于担心在儿童中使用高剂量吸入皮质类固醇（ICS），因此推广了附加治疗。

目的

评估初级保健环境中儿童哮喘药物的处方模式。

方法

使用 2001 年至 2006 年的初级保健数据库对 0-18 岁儿童的哮喘处方进行回顾性观察性研究。

结果

口服皮质类固醇的儿童处方比例显著增加（从 2001-2002 年的 6%增加到 2005-2006 年的 16%，p<0.001），而处方 ICS 剂量>400 mcg 的儿童比例从 16.2%降至 11.7%（P<0.001）。处方附加治疗和 ICS 剂量>400 µg 的儿童比例从 2001-2002 年的 38.8%增加到 2005-2006 年的 61.2%（p<0.001）。