• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

膳食类胡萝卜素对二硝基氟苯诱导的小鼠接触性超敏反应的抑制作用。

Inhibitory effect of dietary carotenoids on dinitrofluorobenzene-induced contact hypersensitivity in mice.

作者信息

Sakai Shota, Sugawara Tatsuya, Hirata Takashi

机构信息

Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.

出版信息

Biosci Biotechnol Biochem. 2011;75(5):1013-5. doi: 10.1271/bbb.110104. Epub 2011 May 20.

DOI:10.1271/bbb.110104
PMID:21597166
Abstract

We evaluated the effect of carotenoids on the dinitrofluorobenzene (DNFB)-induced contact hypersensitivity in mice. Dietary carotenoids significantly inhibited ear swelling and reduced the contents of TNF-α and histamine in the DNFB-treated mice. Our results suggest that dietary carotenoids exerted an anti-inflammatory effect by suppressing mast cell degranulation in vivo.

摘要

我们评估了类胡萝卜素对二硝基氟苯（DNFB）诱导的小鼠接触性超敏反应的影响。膳食类胡萝卜素显著抑制耳部肿胀，并降低DNFB处理小鼠中肿瘤坏死因子-α（TNF-α）和组胺的含量。我们的结果表明，膳食类胡萝卜素通过抑制体内肥大细胞脱颗粒发挥抗炎作用。

相似文献

1
Inhibitory effect of dietary carotenoids on dinitrofluorobenzene-induced contact hypersensitivity in mice.膳食类胡萝卜素对二硝基氟苯诱导的小鼠接触性超敏反应的抑制作用。
Biosci Biotechnol Biochem. 2011;75(5):1013-5. doi: 10.1271/bbb.110104. Epub 2011 May 20.
2
Effect of glucosamine and related compounds on the degranulation of mast cells and ear swelling induced by dinitrofluorobenzene in mice.氨基葡萄糖及其相关化合物对二硝基氟苯诱导的小鼠肥大细胞脱颗粒和耳部肿胀的影响。
Life Sci. 2010 Feb 27;86(9-10):337-43. doi: 10.1016/j.lfs.2010.01.001. Epub 2010 Jan 20.
3
Effect of Sophora flavescens Aiton extract on degranulation of mast cells and contact dermatitis induced by dinitrofluorobenzene in mice.苦参提取物对二硝基氟苯诱导的小鼠肥大细胞脱颗粒及接触性皮炎的影响。
J Ethnopharmacol. 2012 Jun 26;142(1):253-8. doi: 10.1016/j.jep.2012.04.053. Epub 2012 May 9.
4
Effects of astaxanthin on dinitrofluorobenzene-induced contact dermatitis in mice.虾青素对二硝基氟苯诱导的小鼠接触性皮炎的影响。
Mol Med Rep. 2015 Sep;12(3):3632-3638. doi: 10.3892/mmr.2015.3892. Epub 2015 Jun 4.
5
Anti-inflammatory activities of Dictamnus dasycarpus Turcz., root bark on allergic contact dermatitis induced by dinitrofluorobenzene in mice.花椒根皮提取物对角叉菜胶诱导的大鼠足肿胀和二甲苯致小鼠耳肿胀的抗炎作用。
J Ethnopharmacol. 2013 Sep 16;149(2):471-7. doi: 10.1016/j.jep.2013.06.055. Epub 2013 Jul 10.
6
Grape-seed proanthocyanidins ameliorate contact hypersensitivity induced by 2,4-dinitrofluorobenzene (DNFB) and inhibit T cell proliferation in vitro.葡萄籽原花青素可改善 2,4-二硝基氟苯（DNFB）诱导的接触性过敏反应，并抑制体外 T 细胞增殖。
Toxicol Lett. 2012 Apr 5;210(1):1-8. doi: 10.1016/j.toxlet.2012.01.009. Epub 2012 Jan 18.
7
Effects of Schisandra chinensis Turcz. fruit on contact dermatitis induced by dinitrofluorobenzene in mice.五味子果实对二硝基氟苯诱导的小鼠接触性皮炎的影响。
Mol Med Rep. 2015 Aug;12(2):2135-9. doi: 10.3892/mmr.2015.3618. Epub 2015 Apr 15.
8
Divergence of contact hypersensitivity in vivo compared with hapten-specific lymphocyte proliferation and interferon-gamma production in vitro following ultraviolet B irradiation: the possibility that UVB does not affect the sensitizing phase of contact hypersensitivity.紫外线B照射后，体内接触性超敏反应与体外半抗原特异性淋巴细胞增殖及γ-干扰素产生的差异：紫外线B不影响接触性超敏反应致敏阶段的可能性。
Immunology. 2003 Apr;108(4):570-8. doi: 10.1046/j.1365-2567.2003.01602.x.
9
Effect of Scrophularia buergeriana extract on the degranulation of mast cells and ear swelling induced by dinitrofluorobenzene in mice.玄参提取物对二硝基氟苯诱导的小鼠肥大细胞脱颗粒和耳肿胀的影响。
Inflammation. 2012 Feb;35(1):183-91. doi: 10.1007/s10753-011-9304-x.
10
Contact hypersensitivity reactions to dinitrofluorobenzene mediated by monoclonal IgE anti-DNP antibodies.由单克隆IgE抗二硝基苯抗体介导的对二硝基氟苯的接触性超敏反应。
J Immunol. 1983 Sep;131(3):1096-102.

引用本文的文献

1
Advances in Fucoxanthin Research for the Prevention and Treatment of Inflammation-Related Diseases.姜黄素研究进展及其在防治炎症相关疾病中的应用。
Nutrients. 2022 Nov 11;14(22):4768. doi: 10.3390/nu14224768.
2
Fucoxanthin: A Promising Phytochemical on Diverse Pharmacological Targets.岩藻黄质：一种针对多种药理学靶点的有前景的植物化学物质。
Front Pharmacol. 2022 Aug 2;13:929442. doi: 10.3389/fphar.2022.929442. eCollection 2022.
3
Role of Fucoxanthin towards Cadmium-induced renal impairment with the antioxidant and anti-lipid peroxide activities.
姜黄素对镉诱导的肾损伤的作用具有抗氧化和抗脂质过氧化活性。
Bioengineered. 2021 Dec;12(1):7235-7247. doi: 10.1080/21655979.2021.1973875.
4
Black Raspberries and Protocatechuic Acid Mitigate DNFB-Induced Contact Hypersensitivity by Down-Regulating Dendritic Cell Activation and Inhibiting Mediators of Effector Responses.黑覆盆子和原儿茶酸通过下调树突状细胞的激活和抑制效应反应介质来缓解 DNFB 诱导的接触超敏反应。
Nutrients. 2020 Jun 6;12(6):1701. doi: 10.3390/nu12061701.
5
Fucoxanthin, a Marine Xanthophyll Isolated From ND-8: Preventive Anti-Inflammatory Effect in a Mouse Model of Sepsis.岩藻黄质，一种从ND - 8中分离出的海洋叶黄素：在脓毒症小鼠模型中的预防性抗炎作用
Front Pharmacol. 2019 Aug 28;10:906. doi: 10.3389/fphar.2019.00906. eCollection 2019.
6
Siphonaxanthin, a green algal carotenoid, as a novel functional compound.虹吸藻黄素，一种绿藻类胡萝卜素，作为一种新型功能化合物。
Mar Drugs. 2014 Jun 19;12(6):3660-8. doi: 10.3390/md12063660.
7
Peridinin from the marine symbiotic dinoflagellate, Symbiodinium sp., regulates eosinophilia in mice.来自海洋共生甲藻（Symbiodinium sp.）的多甲藻素可调节小鼠的嗜酸性粒细胞增多。
Mar Drugs. 2014 Mar 27;12(4):1773-87. doi: 10.3390/md12041773.
8
Fucoxanthin, a marine carotenoid present in brown seaweeds and diatoms: metabolism and bioactivities relevant to human health.褐藻和硅藻中存在的海洋类胡萝卜素——岩藻黄质：与人类健康相关的代谢和生物活性。
Mar Drugs. 2011;9(10):1806-1828. doi: 10.3390/md9101806. Epub 2011 Oct 10.