Mumu Mumtaza, Das Ayan, Emran Talha Bin, Mitra Saikat, Islam Fahadul, Roy Arpita, Karim Md Mobarak, Das Rajib, Park Moon Nyeo, Chandran Deepak, Sharma Rohit, Khandaker Mayeen Uddin, Idris Abubakr M, Kim Bonglee
Department of Biochemistry and Molecular Biology, Faculty of Biological Sciences, University of Chittagong, Chittagong, Bangladesh.
Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, Bangladesh.
Front Pharmacol. 2022 Aug 2;13:929442. doi: 10.3389/fphar.2022.929442. eCollection 2022.
Fucoxanthin (FX) is a special carotenoid having an allenic bond in its structure. FX is extracted from a variety of algae and edible seaweeds. It has been proved to contain numerous health benefits and preventive effects against diseases like diabetes, obesity, liver cirrhosis, malignant cancer, etc. Thus, FX can be used as a potent source of both pharmacological and nutritional ingredient to prevent infectious diseases. In this review, we gathered the information regarding the current findings on antimicrobial, antioxidant, anti-inflammatory, skin protective, anti-obesity, antidiabetic, hepatoprotective, and other properties of FX including its bioavailability and stability characteristics. This review aims to assist further biochemical studies in order to develop further pharmaceutical assets and nutritional products in combination with FX and its various metabolites.
岩藻黄质（FX）是一种结构中含有丙二烯键的特殊类胡萝卜素。FX从多种藻类和可食用海藻中提取。已证明它具有诸多健康益处，并对糖尿病、肥胖症、肝硬化、恶性肿瘤等疾病具有预防作用。因此，FX可作为预防传染病的强大药理和营养成分来源。在本综述中，我们收集了有关FX的抗菌、抗氧化、抗炎、皮肤保护、抗肥胖、抗糖尿病、肝脏保护等特性以及其生物利用度和稳定性特征的当前研究结果。本综述旨在协助进一步的生化研究，以便结合FX及其各种代谢物开发更多的药物资产和营养产品。
