Clinic for HIV-Related Concerns, Department of Psychiatry, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, 600 University Ave., Rm. 965A, Toronto, ON, M5G 1X5, Canada.
J Behav Med. 2012 Jun;35(3):272-85. doi: 10.1007/s10865-011-9350-8. Epub 2011 May 20.
To determine whether MBSR groups would help gay men living with HIV improve psychosocial functioning and increase mindfulness compared to treatment-as-usual (TAU).
117 participants were randomized 2:1 to MBSR or TAU. No new psychosocial or psychopharmacological interventions were initiated within 2 months of baseline. Standardized questionnaires were administered pre-, postintervention and at 6 months. An intent-to-treat analysis found significant benefits of MBSR: at post-intervention and 6 months follow up, MBSR participants had significantly lower avoidance in IES and higher positive affect compared to controls. MBSR participants developed more mindfulness as measured by the Toronto Mindfulness Scale (TMS) including both TMS subscales, curiosity and decentering, at 8-week and 6 months. For the sample as a whole, increase in mindfulness was significantly correlated with reduction in avoidance, higher positive affect and improvement in depression at 6 months. MBSR has specific and clinically meaningful effects in this population.
目的：确定正念减压疗法（MBSR）小组是否有助于与 HIV 共存的男同性恋者改善心理社会功能，并提高正念水平，与常规治疗（TAU）相比。
方法：117 名参与者按照 2:1 的比例随机分为 MBSR 组或 TAU 组。在基线的 2 个月内，没有启动新的心理社会或精神药理学干预措施。在干预前、干预后和 6 个月时，采用标准化问卷进行评估。意向治疗分析发现 MBSR 有显著益处：在干预后和 6 个月随访时，MBSR 组的 IES 回避得分显著低于对照组，积极情绪得分显著高于对照组。MBSR 组的多伦多正念量表（TMS）评分在 8 周和 6 个月时均有所升高，包括 TMS 两个分量表，即好奇心和去中心化。对于整个样本，6 个月时正念水平的提高与回避减少、积极情绪提高和抑郁改善显著相关。MBSR 在该人群中具有特定且具有临床意义的影响。
