Applied Mycology Unit, Food Technology Department, University of Lleida, XaRTA-UTPV, Av. Rovira Roure 191, E-25198 Lleida, Spain.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011 Aug;28(8):1098-109. doi: 10.1080/19440049.2011.576445. Epub 2011 May 23.
The mycotoxin deoxynivalenol (DON) is one of the most common contaminants of cereals worldwide, and its occurrence has been widely reported in raw foods and foodstuffs, around the European region, including Catalonia. In the present work, a stochastic methodology has been applied to accurately assess the exposure of the Catalonian population (Spain) to DON through food consumption. Raw contamination data was provided by a large survey conducted in this region, in addition to the raw consumption data from a nutritional study specifically designed to assess the dietary intake of the main foodstuffs related to DON contamination for all population age groups. Contamination and consumption data were combined by simulation using an essentially parametric (P-P) method. The P-P method draws sampling values from distribution functions fitted to consumption and contamination data sets. Moreover, to quantify the accuracy and reliability of the statistics estimates, we built the related confidence intervals using a pseudo-parametric bootstrap method. Considering the results drawn from the P-P simulation method, the Catalonian population should be expected to be exposed at moderated levels of deoxynivalenol, the infants and individuals with ethnic dietary patterns being the most exposed population groups.
真菌毒素脱氧雪腐镰刀菌烯醇（DON）是世界范围内谷物中最常见的污染物之一，其在生食品和食品中的存在已在欧洲地区（包括加泰罗尼亚地区）得到广泛报道。在本工作中，采用随机方法准确评估了加泰罗尼亚（西班牙）人群通过食物消费接触 DON 的情况。原始污染数据由该地区进行的一项大型调查提供，此外，还提供了一项专门设计的营养研究的原始消费数据，该研究旨在评估与 DON 污染相关的主要食品的饮食摄入量，涵盖所有年龄组人群。通过模拟使用基本参数（P-P）方法对污染和消费数据进行组合。P-P 方法从与消费和污染数据集拟合的分布函数中抽取采样值。此外，为了量化统计估计的准确性和可靠性，我们使用伪参数引导方法构建了相关的置信区间。根据 P-P 模拟方法得出的结果，预计加泰罗尼亚人群将接触到中度水平的脱氧雪腐镰刀菌烯醇，婴儿和具有民族饮食模式的个体是最易接触到的人群。
