Department of Epidemiology and Biostatistics, School of Public Health, Southeast University, Nanjing, China.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2011 May;28(5):649-58. doi: 10.1080/19440049.2011.563368.
This paper compares the exposure for the Chinese populations and sub-groups to acephate, a widely applied organophosphorus pesticide, using deterministic and probabilistic approaches. Acephate residue data were obtained from the national food contamination monitoring program 2001-2006, collected by multi-stage stratified sampling and with a detection rate of 3.3%. Food consumption data were gathered from the national diet and nutrition survey conducted in 2002 over three consecutive days by the 24-h recall method, and included 22,563 families or 65,886 consumers aged 2-100 years. For point estimate, it was evident that exposures were higher than the acute reference dose (ARfD) in many cases. For the probabilistic approach, the P99.9 exposures for the general population and children accounted for 11.88 and 24.15% of the ARfD, respectively, in acute intake calculations and 52.86 and 68.75%, respectively, of the acceptable daily intake (ADI) in chronic intake calculations. The exposure level of rural people was higher than urban dwellers, and vegetables contributed most to acephate intake.
本文采用确定性和概率两种方法比较了中国人群及其亚组接触广泛使用的有机磷农药——乙酰甲胺磷的情况。2001-2006 年全国食品污染监测计划通过多阶段分层抽样收集了乙酰甲胺磷残留数据，检出率为 3.3%。2002 年通过 24 小时回顾法进行的全国饮食与营养调查收集了食物消费数据，共包括 22563 个家庭或 65886 名 2-100 岁的消费者。就点估计而言，在许多情况下，接触量明显高于急性参考剂量（ARfD）。对于概率方法，在急性摄入量计算中，总人口和儿童的 P99.9 暴露量分别占 ARfD 的 11.88%和 24.15%，在慢性摄入量计算中，分别占可接受日摄入量（ADI）的 52.86%和 68.75%。农村居民的暴露水平高于城镇居民，蔬菜是乙酰甲胺磷摄入量的主要来源。
