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[海马体CA1和CA3区对缺氧状态下延髓呼吸神经元的调节作用]

[Regulatory influence of hippocampus CA1 and CA3 areas on bulbar respiratory neurons under hypoxia].

作者信息

Arutiunian R S, Adamian I Iu, Karapetian M A, Akopian N S

出版信息

Ross Fiziol Zh Im I M Sechenova. 2011 Feb;97(2):169-79.

PMID:21598677
Abstract

We studied the influence of stimulation of the CA1 and CA3 areas of the hippocampus on the impulse activity of respiratory neurons (RN) of the medulla oblongata under normal and oxygen deficiency conditions. Under conditions of normal atmospheric pressure, the electrical stimulation of the CA1 and CA3 areas of the hippocampus had mainly an inhibiting influence. In the initial phase, at a 4-5-thousand meter altitude, activation of frequent discharge of neurons occurred. In this situation, stimulation of the CA1 and CA3 areas was more accentuated than under conditions of normoxia. In the second phase (an altitude of 7.5-8 thousand meters), on the reduction of the impulse activity of neurons, stimulation of the CA1 and CA3 areas of the hippocampus induced untypical responses of these neurons.

摘要

我们研究了在正常和缺氧条件下,刺激海马体CA1区和CA3区对延髓呼吸神经元(RN)冲动活动的影响。在正常大气压条件下,海马体CA1区和CA3区的电刺激主要产生抑制作用。在初始阶段,在海拔4 - 5千米时,神经元放电频率增加。在这种情况下,CA1区和CA3区的刺激比常氧条件下更为明显。在第二阶段(海拔7.5 - 8千米),随着神经元冲动活动的减少,刺激海马体CA1区和CA3区会诱发这些神经元的非典型反应。

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