Department of Surgery, Cairo University Hospitals, Cairo, Egypt.
Am J Surg. 2011 Aug;202(2):133-8. doi: 10.1016/j.amjsurg.2010.06.011. Epub 2011 May 19.
Surgical site infection is a common complication of surgery. Its morbidities range from delayed healing to systemic sepsis. It has impact on the economy and health care resources.
This study was a prospective, randomized, double-blinded, controlled multicenter study aimed to compare triclosan-coated polyglactin 910 sutures with polyglactin 910 sutures for the reduction of surgical site infections. This article details the results from the Cairo University center. A total of 450 patients who had undergone different surgical procedures were enrolled; 230 were enrolled in the study group and 220 were enrolled in the control group.
The study group and the control group were comparable regarding risk factors for surgical site infection. Surgical site infection incidence was 7% in the study group and 15% in the control group (P = .011). The mean extended stay as a result of infection was 3.71 days, with an average cost $91 US per day.
Use of the triclosan-coated polyglactin 910 antimicrobial suture lead to reduction of surgical site infection and has an impact on saving health care resources. The triclosan-coated polyglactin 910 antimicrobial suture could save $1,517,727 yearly in this single center.
手术部位感染是手术的常见并发症。其发病范围从愈合延迟到全身败血症不等。它对经济和医疗资源都有影响。
本研究为前瞻性、随机、双盲、对照多中心研究，旨在比较三氯生涂层聚乳酸 910 缝线与聚乳酸 910 缝线在减少手术部位感染方面的效果。本文详细介绍了开罗大学中心的研究结果。共有 450 名接受不同手术的患者入组；230 名患者入组研究组，220 名患者入组对照组。
研究组和对照组在手术部位感染的危险因素方面具有可比性。研究组手术部位感染发生率为 7%，对照组为 15%（P =.011）。感染导致的平均延长住院时间为 3.71 天，平均每天费用为 91 美元。
使用三氯生涂层聚乳酸 910 抗菌缝线可降低手术部位感染的发生率，并对节约医疗资源有影响。在单中心层面，这种三氯生涂层聚乳酸 910 抗菌缝线每年可节省 151.7727 万美元。
