Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.
J Am Acad Dermatol. 2012 Mar;66(3):e97-102. doi: 10.1016/j.jaad.2010.11.042. Epub 2011 May 24.
Hair loss may significantly impact an individual's self-image, and studies indicate that patients with both clinically apparent and clinically imperceptible hair loss may have significantly decreased quality of life (QoL). Moreover, clinical severity of hair loss does not necessarily predict impact on QoL.
The aim of this study was to assess QoL in patients (n = 104) with alopecia areata, telogen effluvium, and androgenic alopecia, and to compare QoL with hair loss severity (HLS) as independently rated by both patient and dermatologist.
Questionnaires and clinical assessment tools were used to assess HLS, and QoL was measured by completion of Skindex-16.
Overall, patients rated their hair loss as more severe than the dermatologist, and the patient's HLS rating more strongly correlated with QoL than the dermatologist's rating. Clinical assessment of HLS did not reliably predict the patient's QoL, nor did it predict the patient's perception of HLS.
A convenience sample was recruited from a referral clinic and Skindex-16 has not been validated for use in women's alopecia disorders.
These findings indicate dermatologists should address these psychosocial and QoL issues when treating patients with alopecia.
脱发可能会严重影响个人形象，研究表明，患有临床明显和临床不可察觉的脱发的患者生活质量（QoL）可能会显著降低。此外，脱发的临床严重程度不一定能预测对 QoL 的影响。
本研究旨在评估斑秃、休止期脱发和雄激素性脱发患者（n=104）的 QoL，并比较患者和皮肤科医生独立评估的脱发严重程度（HLS）与 QoL 的关系。
使用问卷和临床评估工具评估 HLS，并通过完成 Skindex-16 来测量 QoL。
总体而言，患者认为自己的脱发比皮肤科医生严重，患者的 HLS 评分与 QoL 的相关性强于皮肤科医生的评分。HLS 的临床评估不能可靠地预测患者的 QoL，也不能预测患者对 HLS 的感知。
从转诊诊所招募了一个方便样本，并且 Skindex-16 尚未在女性脱发疾病中得到验证。
这些发现表明，皮肤科医生在治疗脱发患者时应解决这些心理社会和 QoL 问题。
