UCD School of Chemical and Bioprocess Engineering, Centre for Synthesis and Chemical Biology, University College Dublin, Dublin, Ireland.
J Hosp Infect. 2011 Jul;78(3):204-7. doi: 10.1016/j.jhin.2011.03.019. Epub 2011 May 23.
The effective disinfection of hospital surfaces is recognised as an important factor in preventing hospital-acquired infections. The purpose of this study was to quantify the disinfection rate of a novel gas plasma system on clinically relevant biofilms. Clinical isolates of Staphylococcus epidermidis and meticillin-resistant Staphylococcus aureus (MRSA) were grown as biofilms on glass surfaces and tested in a disinfection container remote from the plasma source. The strains used in this study were known to produce substantial quantities of biofilm and average log₁₀ counts were 9.0 and 9.1 cfu/cm(2) for S. epidermidis and MRSA respectively. Counts were reduced by between 4 and 4.5 log₁₀ after 1h of exposure for MRSA and S. epidermidis respectively. More prolonged treatment in the case of MRSA biofilms resulted in a 5.5 log₁₀ reduction after 90 min. Biofilm samples were also placed in medical device packaging bags and similar rates of disinfection were observed.
医院表面的有效消毒被认为是预防医院获得性感染的一个重要因素。本研究的目的是量化一种新型气体等离子体系统对临床相关生物膜的消毒率。表皮葡萄球菌和耐甲氧西林金黄色葡萄球菌（MRSA）的临床分离株在玻璃表面上形成生物膜，并在远离等离子体源的消毒容器中进行测试。本研究中使用的菌株已知会产生大量生物膜，表皮葡萄球菌和 MRSA 的平均对数 10 计数分别为 9.0 和 9.1 cfu/cm²。MRSA 和表皮葡萄球菌分别在 1 小时的暴露后减少了 4 到 4.5 个对数 10。对于 MRSA 生物膜，延长处理时间会导致 90 分钟后减少 5.5 个对数 10。生物膜样本也被放置在医疗器械包装袋中，观察到类似的消毒率。
