China Institute of Veterinary Drug Control, Beijing 100081, People’s Republic of China.
J Bacteriol. 2011 Jul;193(14):3674-5. doi: 10.1128/JB.05155-11. Epub 2011 May 20.
Brucella melitensis and Brucella suis are intracellular pathogens of livestock and humans. Here we report four genome sequences, those of the virulent strain B. melitensis M28-12 and vaccine strains B. melitensis M5 and M111 and B. suis S2, which show different virulences and pathogenicities, which will help to design a more effective brucellosis vaccine.
绵羊布鲁氏菌和猪布鲁氏菌是家畜和人类的细胞内病原体。在这里,我们报告了 4 个基因组序列,分别来自毒力株布鲁氏菌 M28-12 以及疫苗株布鲁氏菌 M5、M111 和猪布鲁氏菌 S2。这些菌株的毒力和致病性不同,这将有助于设计更有效的布鲁氏菌病疫苗。