α(2) 激动剂在神经麻醉中的应用：概述
Use of α(2)-Agonists in Neuroanesthesia: An Overview.
作者信息
Farag Ehab, Argalious Maged, Sessler Daniel I, Kurz Andrea, Ebrahim Zeyd Y, Schubert Armin
出版信息
Ochsner J. 2011 Spring;11(1):57-69.
Abstract
α(2)-Agonists are a novel class of drugs with mechanisms of action that differ from other commonly used anesthetic drugs. They have neuroprotective, cardioprotective, and sedative effects. These unique characteristics make them potentially useful during neuroanesthesia and intensive care. We review the effects of dexmedetomidine on cerebral blood flow and cerebral metabolism, along with recent advances in using α(2)-agonists in neuroanesthesia and neurointensive care.
摘要
α(2)激动剂是一类新型药物，其作用机制不同于其他常用麻醉药物。它们具有神经保护、心脏保护和镇静作用。这些独特特性使其在神经麻醉和重症监护期间具有潜在用途。我们综述了右美托咪定对脑血流和脑代谢的影响，以及在神经麻醉和神经重症监护中使用α(2)激动剂的最新进展。
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