Sport and Exercise Sciences Research Institute, University of Ulster, Jordanstown, Belfast, BT37 OQB, UK.
Eur J Appl Physiol. 2012 Feb;112(2):781-8. doi: 10.1007/s00421-011-2003-3. Epub 2011 May 21.
The combined effects of 42 days of chronic sleep disruption and repeated hourly bouts of physical exertion have not been described. This case study reports the physiological and psychological demands placed on one individual who walked 1 mile in each consecutive hour for a period of 1,000 h (42 days), covering a total distance of 1,000 miles. The participant walked at a mean speed of 1.75 m/s completing each mile in approximately 15 min. Over the course of the challenge, the individual lost 1.6 kg in body weight. Markers of skeletal muscle damage, increased gradually whilst free testosterone levels decreased over the course of the challenge. Stress hormones increased whilst inflammatory markers (CRP) initially rose but then returned towards baseline over the course of the study. Cognitive motor performance measured via reaction time was maintained throughout the 42 days. The participant also displayed mood states typical of an elite athlete at baseline and throughout the challenge. Participation in this novel '1,000 mile 1,000 h' walking challenge evoked considerable physiological stress in a fit, healthy middle-aged participant but did not markedly alter cognitive performance or mood over the 42-day period.
尚未描述 42 天慢性睡眠中断和反复每小时体力消耗的综合影响。本案例研究报告了一名个体在 1000 小时（42 天）期间连续每小时行走 1 英里所承受的生理和心理需求，总距离为 1000 英里。参与者以平均 1.75 米/秒的速度行走，每英里大约用时 15 分钟。在挑战过程中，个体体重减轻了 1.6 公斤。骨骼肌肉损伤标志物逐渐增加，而游离睾酮水平在整个挑战过程中下降。应激激素增加，而炎症标志物（CRP）最初升高，但随后在研究过程中恢复到基线水平。通过反应时间测量的认知运动表现整个 42 天都保持不变。参与者在基线和整个挑战过程中也表现出典型的优秀运动员的情绪状态。在一个健康的中年参与者中进行这种新颖的“1000 英里 1000 小时”步行挑战会引起相当大的生理压力，但在 42 天内不会明显改变认知表现或情绪。
