Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, University of California at Los Angeles, Los Angeles, California, USA.
Clin Pharmacol Ther. 2010 Apr;87(4):479-82. doi: 10.1038/clpt.2009.255. Epub 2010 Feb 3.
This review focuses on the biobehavioral factors that show robust associations with markers of inflammation and discusses the following variables: diet, smoking, coffee, alcohol, exercise, and sleep disruption. Each of these variables has been assessed in large-scale epidemiological studies, and many of them have been assessed in clinical and experimental studies as well. Treatment strategies that target biobehavioral factors have the potential to complement and enhance the benefit of anti-inflammatory medicines.
这篇综述重点关注与炎症标志物具有强相关性的生物行为因素,并讨论了以下变量:饮食、吸烟、咖啡、酒精、运动和睡眠障碍。这些变量中的每一个都在大规模的流行病学研究中进行了评估,其中许多也在临床和实验研究中进行了评估。针对生物行为因素的治疗策略有可能补充和增强抗炎药物的疗效。