Department of Sports Medicine, Prevention and Rehabilitation, Paracelsus Medical University, Salzburg, Austria.
Am J Med. 2011 Jun;124(6):489-97. doi: 10.1016/j.amjmed.2011.01.015.
Since the discovery of endothelial progenitor cells in 1997, the scientific world has seen their ups and downs. There has been much discussion about the detection methods of endothelial progenitor cells and their diagnostic and predictive value. A lack of standardized methods to define endothelial progenitor cells has led to a number of nomenclatures and measuring methods that are difficult for clinicians to oversee. Therefore, only specialized hematologists and cardiologists were aware of their existence. Now it is time for a change: Most of the controversies have been eliminated by elaborate studies. This review aims to give an overview to the clinically working physician about the measurement, diagnostic potential, predictive value, and therapeutic potential of endothelial progenitor cells.
自 1997 年发现内皮祖细胞以来，科学界对其经历了起起落落。人们对内皮祖细胞的检测方法及其诊断和预测价值进行了大量讨论。由于缺乏标准化的方法来定义内皮祖细胞，因此出现了许多命名法和测量方法，这使得临床医生难以掌握。因此，只有专门的血液学家和心脏病学家才知道它们的存在。现在是改变的时候了：精心设计的研究消除了大部分争议。本篇综述旨在为临床工作的医生提供有关内皮祖细胞的测量、诊断潜力、预测价值和治疗潜力的概述。
