Department of Oral and Maxillofacial Surgery, Okitama Public General Hospital, Ooazanishiootsuka 2000, Kawanishi-machi, Higashiokitama-gun, Yamagata, 992-0601, Japan.
Odontology. 2012 Jan;100(1):104-8. doi: 10.1007/s10266-011-0027-0. Epub 2011 May 24.
Lipoma is relatively uncommon in the oral cavity. Among the intraoral regions, lipoma involving the gingiva or gingivobuccal fold is relatively infrequent. We report the case of a patient with lipoma extending superiorly from the mandibular gingivobuccal fold to the gingiva. In addition to the case report, we retrospectively reviewed 207 patients with intraoral lipoma reported in Japan from 1987 to 2004. The most frequent site of development was the buccal mucosa (40.6%), followed by the tongue (17.9%), lip (12.6%), gingiva (8.7%), oral floor (6.8%), gingivobuccal fold and palate (4.8%), and others (3.9%). Occurrence tended to be more frequent in males (57.5%) than in females (42.5%). Relative to age, frequency peaked among patients in the 7th (27.3%) and 6th decades (25.1%), respectively, followed in descending order by the 5th (14.8%) and 8th decades (13.1%). The majority of patients (86.3%) were at least 40 years. The most frequent size was 10-19 mm (37.5%), followed by 0-9 mm (27.8%) and 20-29 mm (14.6%), and tumors 30 mm or larger were relatively infrequent. Histopathological types in order of descending frequency were lipomas (69.0%), fibrolipomas (27.4%), and others (3.5%). The male:female ratio was 1.7:1 for lipoma and 1:1.6 for fibrolipoma.
口腔内的脂肪瘤相对少见。在口腔内各部位中，发生于牙龈或颊龈皱褶的脂肪瘤则较为罕见。我们报告了一例源自下颌颊龈皱褶向牙龈上方延伸的脂肪瘤患者。除病例报告外，我们还回顾性分析了 1987 年至 2004 年日本报道的 207 例口腔内脂肪瘤患者。最常见的发病部位是颊黏膜（40.6%），其次是舌（17.9%）、唇（12.6%）、牙龈（8.7%）、口腔底部（6.8%）、颊龈皱褶和腭部（4.8%）以及其他部位（3.9%）。男性（57.5%）发病倾向高于女性（42.5%）。与年龄相关，70 岁（27.3%）和 60 岁（25.1%）两个年龄段发病率最高，随后发病率依次下降，分别为 50 岁（14.8%）和 80 岁（13.1%）。大多数患者（86.3%）年龄至少 40 岁。最常见的肿瘤大小为 10-19mm（37.5%），其次是 0-9mm（27.8%）和 20-29mm（14.6%），30mm 或更大的肿瘤相对少见。按发病率降序排列，组织病理学类型依次为脂肪瘤（69.0%）、纤维脂肪瘤（27.4%）和其他类型（3.5%）。脂肪瘤的男女发病比例为 1.7:1，纤维脂肪瘤为 1:1.6。
