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在接受含HIV抗体的抗-D免疫球蛋白的受者中,缺乏血清转化为人类免疫缺陷病毒的证据。

Lack of evidence for seroconversion to human immunodeficiency virus in recipients of anti-D immunoglobulin containing HIV antibody.

作者信息

Babu P G, Cherian T, Jairaj P K, Jayakumari H, John T J

机构信息

Department of Virology & Immunology, Christian Medical College Hospital, Vellore.

出版信息

Indian J Med Res. 1990 Mar;91:81-3.

PMID:2160915
Abstract

Twenty nine Rh negative women who had received injections of anti-D (Rho) immunoglobulin preparations (from an Indian firm) contaminated with antibody to human immunodeficiency virus (HIV), were tested for seroconversion to HIV, 14-38 wk after injections. All 29 were negative for HIV antibody, indicating that infectious HIV or immunogenic concentrations of inactivated HIV were not present in the investigated immunoglobulin product.

摘要

29名接受了抗D(Rho)免疫球蛋白制剂(来自一家印度公司)注射的Rh阴性女性,这些制剂被人类免疫缺陷病毒(HIV)抗体污染,在注射后14 - 38周接受了HIV血清转化检测。所有29人HIV抗体均为阴性,这表明在所研究的免疫球蛋白产品中不存在具有传染性的HIV或免疫原性浓度的灭活HIV。

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