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F-FDG PET/CT作为MRI在鉴别布罗迪脓肿方面潜在的有价值辅助手段。

F-FDG PET/CT as a potential valuable adjunct to MRI in characterising the Brodie's abscess.

作者信息

Fathinul F, Nordin Aj

机构信息

Damai Service Hospital, Jalan Ipoh, Kuala Lumpur, Malaysia.

出版信息

Biomed Imaging Interv J. 2010 Jul-Sep;6(3):e26. doi: 10.2349/biij.6.3.e26. Epub 2010 Jul 1.

Abstract

Chronic osteomyelitis (Brodie's abscess) is essentially a problem of diagnosis, and there may be considerable difficulty in distinguishing it from other benign and malignant bone lesions. Early diagnosis of Brodie's abscess is deemed important as the disease has a good curative potential following an appropriate antibiotic treatment. Of late, PET/CT using (18)F-FDG is taking a centre stage in the imaging of bone infection though documentation on its role in characterising the feature of Brodie's abscess is exceedingly scarce. On the other hand, it is well known that MRI imaging plays a very important role in distinguishing abscess loculation from malignancy. The authors present the case of a 13-year-old boy with pain in the right heel for few months. Radiograph of the right foot revealed a lucent focus with sclerotic margin in the right calcaneum. MRI T1-weighted images were inconclusive of penumbra sign to characterise abscess cavity due to the small volume lesion. Whole-body (18)F-FDG PET/CT scan showed multiple small avid lesions at the margin of the sclerotic rim in the right calcaneum. Final diagnosis of Brodie's abscess with Klebsiella culture was confirmed via bone debridement.

摘要

慢性骨髓炎(布罗迪氏骨脓肿)本质上是一个诊断问题,要将其与其他良恶性骨病变区分开来可能有相当大的困难。布罗迪氏骨脓肿的早期诊断被认为很重要,因为经过适当的抗生素治疗后,该病具有良好的治愈潜力。近年来,使用(18)F-FDG的PET/CT在骨感染成像中占据了核心地位,不过关于其在描述布罗迪氏骨脓肿特征方面作用的文献极为稀少。另一方面,众所周知,MRI成像在区分脓肿形成与恶性肿瘤方面起着非常重要的作用。作者报告了一例13岁男孩,右足跟疼痛数月。右脚X线片显示右跟骨有一个边缘硬化的透亮病灶。由于病灶体积小,MRI T1加权图像无法确定半影征以表征脓肿腔。全身(18)F-FDG PET/CT扫描显示右跟骨硬化边缘处有多个小的放射性浓聚病灶。通过骨清创术确诊为克雷伯菌培养阳性的布罗迪氏骨脓肿。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e41/3097771/6ea63fd125db/biij-06-e26-g01.jpg

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