Crawford C L, Hardwicke P M
Acta Neuropathol. 1979 Jan 12;45(1):1-7. doi: 10.1007/BF00691798.
Rabbits previously sensitised by injection of human sensory peripheral nerve showed degeneration of somatic unmyelinated fibres at skin test sites when challenged by sensory nerve or certain non-myelin fractions prepared from human sensory nerve. Epithelioid cells were found in the endoneurium and may mediate the nerve damage. The degeneration was consistently found and lasted for at least 58 days. Phagocytosing macrophages were absent. Differences in the pattern of nerve damage to that of EAN and EAE are discussed.
通过注射人感觉外周神经预先致敏的兔子，当受到感觉神经或从人感觉神经制备的某些无髓鞘组分攻击时，在皮肤试验部位出现躯体无髓鞘纤维变性。在内神经膜中发现了上皮样细胞，其可能介导神经损伤。这种变性持续存在，至少持续58天。未见吞噬性巨噬细胞。文中讨论了与实验性变态反应性神经炎（EAN）和实验性自身免疫性脑脊髓炎（EAE）神经损伤模式的差异。
