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Moloney murine leukemia virus temperature-sensitive mutants: a model for retrovirus-induced neurologic disorders.

作者信息

Wong P K

机构信息

University of Texas, MD Anderson Cancer Center, Smithville 78957.

出版信息

Curr Top Microbiol Immunol. 1990;160:29-60. doi: 10.1007/978-3-642-75267-4_3.

DOI:10.1007/978-3-642-75267-4_3
PMID:2162285
Abstract
摘要

相似文献

1
Moloney murine leukemia virus temperature-sensitive mutants: a model for retrovirus-induced neurologic disorders.莫洛尼鼠白血病病毒温度敏感突变体:逆转录病毒诱导的神经系统疾病模型。
Curr Top Microbiol Immunol. 1990;160:29-60. doi: 10.1007/978-3-642-75267-4_3.
2
Leukemogenesis by Moloney murine leukemia virus: a multistep process.莫洛尼鼠白血病病毒引发白血病:一个多步骤过程。
Trends Microbiol. 1997 Feb;5(2):74-82. doi: 10.1016/S0966-842X(96)10076-7.
3
ts1, a mutant of Moloney murine leukemia virus-TB, causes both immunodeficiency and neurologic disorders in BALB/c mice.
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4
Identification of point mutations in the envelope gene of Moloney murine leukemia virus TB temperature-sensitive paralytogenic mutant ts1: molecular determinants for neurovirulence.莫洛尼鼠白血病病毒TB温度敏感致瘫突变体ts1包膜基因点突变的鉴定:神经毒力的分子决定因素
J Virol. 1988 Jan;62(1):357-60. doi: 10.1128/JVI.62.1.357-360.1988.
5
A Moloney murine leukemia virus-based retrovirus with 4070A long terminal repeat sequences induces a high incidence of myeloid as well as lymphoid neoplasms.一种带有4070A长末端重复序列的莫洛尼鼠白血病病毒衍生的逆转录病毒可诱发高发性的髓系和淋巴系肿瘤。
J Virol. 2003 Apr;77(8):4965-71. doi: 10.1128/jvi.77.8.4965-4971.2003.
6
Rudimentary thymus of SCID mouse plays an important role in the development of retrovirus-induced neurologic disorders.重症联合免疫缺陷(SCID)小鼠的原始胸腺在逆转录病毒诱导的神经疾病发展中起重要作用。
Virology. 1993 Jul;195(1):211-8. doi: 10.1006/viro.1993.1362.
7
Transmission of Moloney murine leukemia virus (ts-1) by breast milk.
J Gen Virol. 2006 Sep;87(Pt 9):2679-2684. doi: 10.1099/vir.0.82015-0.
8
Substitution of feline leukemia virus long terminal repeat sequences into murine leukemia virus alters the pattern of insertional activation and identifies new common insertion sites.将猫白血病病毒长末端重复序列替换到鼠白血病病毒中会改变插入激活模式并识别出新的常见插入位点。
J Virol. 2005 Jan;79(1):57-66. doi: 10.1128/JVI.79.1.57-66.2005.
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Astrocytes survive chronic infection and cytopathic effects of the ts1 mutant of the retrovirus Moloney murine leukemia virus by upregulation of antioxidant defenses.星形胶质细胞通过上调抗氧化防御机制,在感染逆转录病毒莫洛尼鼠白血病病毒ts1突变体的慢性感染及细胞病变效应中存活下来。
J Virol. 2006 Apr;80(7):3273-84. doi: 10.1128/JVI.80.7.3273-3284.2006.
10
Alteration from T- to B-cell tropism reduces thymic atrophy and cytocidal effects in thymocytes but not neurovirulence induced by ts1, a mutant of Moloney murine leukemia virus TB.
Proc Natl Acad Sci U S A. 1991 Oct 15;88(20):8991-5. doi: 10.1073/pnas.88.20.8991.

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MoMuLV-ts-1: A Unique Mouse Model of Retrovirus-Induced Lymphoma Transmitted by Breast Milk.莫洛尼鼠白血病病毒温度敏感株1:一种通过母乳传播的逆转录病毒诱导淋巴瘤的独特小鼠模型。
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Neuroprotective effects of the drug GVT (monosodium luminol) are mediated by the stabilization of Nrf2 in astrocytes.
药物 GVT(单钠鲁米诺)的神经保护作用是通过稳定星形胶质细胞中的 Nrf2 来介导的。
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Attenuation of oxidative stress, inflammation and apoptosis by minocycline prevents retrovirus-induced neurodegeneration in mice.米诺环素减轻氧化应激、炎症和细胞凋亡,从而预防逆转录病毒诱导的小鼠神经退行性变。
Brain Res. 2009 Aug 25;1286:174-84. doi: 10.1016/j.brainres.2009.06.007. Epub 2009 Jun 11.
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Retrovirus-induced oxidative stress with neuroimmunodegeneration is suppressed by antioxidant treatment with a refined monosodium alpha-luminol (Galavit).逆转录病毒诱导的伴有神经免疫退变的氧化应激可通过用精制α-鲁米诺单钠(加拉维特)进行抗氧化治疗得到抑制。
J Virol. 2006 May;80(9):4557-69. doi: 10.1128/JVI.80.9.4557-4569.2006.
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Astrocytes survive chronic infection and cytopathic effects of the ts1 mutant of the retrovirus Moloney murine leukemia virus by upregulation of antioxidant defenses.星形胶质细胞通过上调抗氧化防御机制,在感染逆转录病毒莫洛尼鼠白血病病毒ts1突变体的慢性感染及细胞病变效应中存活下来。
J Virol. 2006 Apr;80(7):3273-84. doi: 10.1128/JVI.80.7.3273-3284.2006.
7
Rodent model systems for studies of HIV-1 associated dementia.用于研究HIV-1相关性痴呆的啮齿动物模型系统。
Neurotox Res. 2005 Oct;8(1-2):91-106. doi: 10.1007/BF03033822.
8
Protection against murine leukemia virus-induced spongiform myeloencephalopathy in mice overexpressing Bcl-2 but not in mice deficient for interleukin-6, inducible nitric oxide synthetase, ICE, Fas, Fas ligand, or TNF-R1 genes.过表达Bcl-2的小鼠对鼠白血病病毒诱导的海绵状脊髓脑病具有抵抗力,但白细胞介素-6、诱导型一氧化氮合酶、ICE、Fas、Fas配体或TNF-R1基因缺陷的小鼠则不然。
J Virol. 2003 Dec;77(24):13161-70. doi: 10.1128/jvi.77.24.13161-13170.2003.
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Effects of mutant ubiquitin on ts1 retrovirus-mediated neuropathology.突变泛素对ts1逆转录病毒介导的神经病理学的影响。
J Virol. 2003 Jul;77(13):7193-201. doi: 10.1128/jvi.77.13.7193-7201.2003.
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J Virol. 2000 Jan;74(1):465-73. doi: 10.1128/jvi.74.1.465-473.2000.