Weigler B J, Roberts J A, Hird D W, Lerche N W, Hilliard J K
Department of Epidemiology and Preventive Medicine, School of Veterinary Medicine, University of California, Davis 95616.
Lab Anim Sci. 1990 May;40(3):257-61.
A systematic sampling technique was used in combination with a highly sensitive and specific ELISA to provide unbiased age-specific prevalence estimates of B virus antibody in rhesus monkeys housed in three different outdoor breeding corrals. Among 146 sampled monkeys, 97% of animals 2.5 years and older were seropositive, while only 22% of younger animals were seropositive. Neither gender nor social dominance ranking were predictive of B virus antibody status. The strong age association was not inconsistent with hypothesized venereal transmission of B virus. Improvements in the epidemiologic understanding of B virus are necessary to assist efforts to eradicate this agent from breeding colonies of rhesus monkeys.
采用系统抽样技术并结合高灵敏度和特异性的酶联免疫吸附测定（ELISA），以提供在三个不同户外繁殖围栏中饲养的恒河猴B病毒抗体的无偏倚年龄特异性流行率估计值。在146只抽样猴子中，2.5岁及以上的动物中有97%血清呈阳性，而较年轻的动物中只有22%血清呈阳性。性别和社会优势等级都不能预测B病毒抗体状态。这种强烈的年龄关联与B病毒通过性传播的假设并不矛盾。有必要改善对B病毒的流行病学认识，以协助从恒河猴繁殖群体中根除这种病原体的工作。
