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[垂体-肾上腺皮质系统功能改变的大鼠血浆中铜蓝蛋白和转铁蛋白的电子顺磁共振信号强度]

[The signal intensity of the electron paramagnetic resonance of ceruloplasmin and transferrin in the blood plasma of rats with altered function of the hypophyseal-adrenal cortex system].

作者信息

Kandul S V, Iatsyk M I, Tiuleneva G V

出版信息

Probl Endokrinol (Mosk). 1990 Mar-Apr;36(2):80-3.

PMID:2163530
Abstract

The paper is concerned with the experimental data on a ERP signal size in two blood plasma metalloproteins--ceruloplasmin and transferrin and their correlations after intraperitoneal hydrocortisone and corticotropin injections (5 mg and 2.5 U/100 g body weight, respectively) to Wistar adult male rats and after bilateral adrenalectomy. A conclusion has been made that antioxidant activity of the ceruloplasmin-transferrin complex in rat blood plasma is increased with a rise of the corticotropin level but it is decreased with hydrocortisone loading.

摘要

本文关注的是成年雄性Wistar大鼠腹腔注射氢化可的松和促肾上腺皮质激素(分别为5mg和2.5U/100g体重)以及双侧肾上腺切除术后,两种血浆金属蛋白酶——铜蓝蛋白和转铁蛋白中ERP信号大小的实验数据及其相关性。得出的结论是,大鼠血浆中铜蓝蛋白 - 转铁蛋白复合物的抗氧化活性随促肾上腺皮质激素水平升高而增加,但随氢化可的松负荷增加而降低。

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