Kandul S V, Iatsyk M I, Tiuleneva G V
Probl Endokrinol (Mosk). 1990 Mar-Apr;36(2):80-3.
The paper is concerned with the experimental data on a ERP signal size in two blood plasma metalloproteins--ceruloplasmin and transferrin and their correlations after intraperitoneal hydrocortisone and corticotropin injections (5 mg and 2.5 U/100 g body weight, respectively) to Wistar adult male rats and after bilateral adrenalectomy. A conclusion has been made that antioxidant activity of the ceruloplasmin-transferrin complex in rat blood plasma is increased with a rise of the corticotropin level but it is decreased with hydrocortisone loading.
本文关注的是成年雄性Wistar大鼠腹腔注射氢化可的松和促肾上腺皮质激素(分别为5mg和2.5U/100g体重)以及双侧肾上腺切除术后,两种血浆金属蛋白酶——铜蓝蛋白和转铁蛋白中ERP信号大小的实验数据及其相关性。得出的结论是,大鼠血浆中铜蓝蛋白 - 转铁蛋白复合物的抗氧化活性随促肾上腺皮质激素水平升高而增加,但随氢化可的松负荷增加而降低。