Kakou Guikahué M, Chauvet J, Seka R, Yapobi Y, Ake E, Kroo Aka F, Ekra A, Kachaner J, Bertrand E
Institut de cardiologie, Abidjan, République de Cŏte-d'Ivoire.
Arch Mal Coeur Vaiss. 1990 May;83(5):723-8.
During the last 10 years, 17 children with transposition of the great arteries (TGA) were admitted to the Cardiology Institute of Abidjan: 1 case between March 1978 and December 1985, 16 cases between January 1986 and December 1989. The average age was 58 days (range 5 to 270 days) at the first consultation, and 90 days (5 to 270 days) at the time of admission. The diagnosis was confirmed by echocardiography and hemodynamic investigation in 12 cases. There were 9 simple forms of TGA, 7 with ventricular septal defects (VSD) and 1 with VSD and pulmonary stenosis. Two children were taken back by their parents before any treatment was given. A Rashkind atrial septostomy was carried out in 11 children which increased aortic oxygen saturation from 35 +/- 18 percent to 57 +/- 19 percent; there were 3 unsuccessful procedures in children aged 2, 3 and 5 months with 2 deaths. Five patients later underwent surgical correction by a Senning procedure in 4 cases and anatomical correction in 1 case with VSD. All are well after an average 15 months follow-up (1 to 48 months). One of the 8 children awaiting surgery died. Therefore, TGA is not a rare abnormality in Black Africa; it represents 2 percent of the 887 cases of congenital heart disease observed during the same period. The inadequacy of means of diagnosis is certainly the cause of the relatively low incidence of this malformation, of the considerable delay in under specialist care and, as a consequence, of the greater difficulties in treatment, especially with regards to atrial septostomy.(ABSTRACT TRUNCATED AT 250 WORDS)
在过去10年中,17例患有大动脉转位(TGA)的儿童被收治于阿比让心脏病研究所:1978年3月至1985年12月有1例,1986年1月至1989年12月有16例。首次就诊时平均年龄为58天(范围5至270天),入院时平均年龄为90天(5至270天)。12例通过超声心动图和血流动力学检查确诊。有9例单纯型TGA,7例伴有室间隔缺损(VSD),1例伴有VSD和肺动脉狭窄。2名儿童在未接受任何治疗前被父母带回。11名儿童进行了 Rashkind 房间隔造口术,主动脉血氧饱和度从35±18%提高到57±19%;2、3和5个月大的儿童中有3例手术失败,2例死亡。5例患者后来接受了手术矫正,4例行 Senning 手术,1例伴有VSD的行解剖矫正。平均随访15个月(1至48个月)后均情况良好。8名等待手术的儿童中有1例死亡。因此,TGA在黑非洲并非罕见的异常情况;它占同期观察到的887例先天性心脏病病例的2%。诊断手段不足肯定是这种畸形发病率相对较低、专科护理严重延迟以及因此治疗难度更大的原因,尤其是在房间隔造口术方面。(摘要截取自250字)