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原发性恶性肿瘤和非小细胞肺癌脑转移中 F-18 氟化物的骨外摄取。

Extraosseus uptake of F-18 fluoride in the primary malignancy and cerebral metastasis in a case of non-small-cell lung cancer.

机构信息

VA Greater Los Angeles Healthcare System, Department of Nuclear Medicine, Los Angeles, CA 90073, USA.

出版信息

Clin Nucl Med. 2011 Jul;36(7):609-11. doi: 10.1097/RLU.0b013e318217af49.

DOI:10.1097/RLU.0b013e318217af49
PMID:21637076
Abstract

A 68-year-old man with history of heavy smoking was admitted for increasing falls during the past 4 weeks. Chest x-ray revealed a right upper lobe mass. Biopsy demonstrated poorly differentiated non-small-cell carcinoma. F-18 fluoride positron emission tomography/computer tomography (PET/CT) was performed to evaluate bone metastasis. Review of the sectional PET images demonstrated extraosseous fluoride uptake in the primary lung mass, as well as ring-shaped fluoride uptake in the cerebral metastatic lesion. Neither of these lesions demonstrated calcifications on CT images. The patient received radiation treatment of the brain metastasis after F-18 fluoride PET/CT study.

摘要

一位 68 岁男性,有重度吸烟史,因过去 4 周内频繁跌倒而入院。胸部 X 光片显示右上肺肿块。活检显示低分化非小细胞癌。进行 F-18 氟化物正电子发射断层扫描/计算机断层扫描(PET/CT)以评估骨转移。回顾性分析 PET 断层图像显示原发性肺肿块有骨外氟摄取,以及脑转移病灶有环形氟摄取。这两个病灶在 CT 图像上均未见钙化。氟 18 正电子发射断层扫描/计算机断层扫描(PET/CT)检查后,患者接受了脑部转移灶的放射治疗。

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