Pogozelski Wendy, Arpaia Nicholas, Priore Salvatore
Department of Chemistry, State University of New York College at Geneseo, Geneseo, New York 14454.
Biochem Mol Biol Educ. 2005 Mar;33(2):91-100. doi: 10.1002/bmb.2005.494033022445.
One of the challenges in teaching biochemistry is facilitating students' interest in and mastery of metabolism. The many pathways and modes of regulation can be overwhelming for students to learn and difficult for professors to teach in an engaging manner. We have found it useful to take advantage of prevailing interest in popular yet controversial weight-loss methods, particularly low-carbohydrate diets. The metabolic rationale behind these eating plans can be linked to glycolysis, the citric acid cycle, lipolysis, gluconeogenesis, ketosis, glycogen metabolism, fatty acid oxidation, and hormonal regulation. When this approach was used in undergraduate biochemistry classes at the State University of New York at Geneseo, students were highly motivated to learn the biochemical principles behind these diets. The following provides information about low-carbohydrate diet plans that will enable professors to speak authoritatively on the subject. History and studies regarding efficacy as well as biochemical metabolic effects are included.
生物化学教学面临的挑战之一是激发学生对新陈代谢的兴趣并使其掌握相关知识。众多的代谢途径和调节方式让学生学习起来应接不暇，教授们也难以生动有趣地进行讲授。我们发现利用当下人们对流行但颇具争议的减肥方法，尤其是低碳水化合物饮食的普遍兴趣很有帮助。这些饮食计划背后的代谢原理可以与糖酵解、柠檬酸循环、脂肪分解、糖异生、酮症、糖原代谢、脂肪酸氧化以及激素调节联系起来。当这种方法在纽约州立大学杰纳苏分校的本科生物化学课程中使用时，学生们学习这些饮食背后生化原理的积极性很高。以下提供了有关低碳水化合物饮食计划的信息，这将使教授们能够权威地谈论这个话题。其中包括关于功效的历史和研究以及生化代谢效应。
