Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
Neuroimaging Clin N Am. 2011 May;21(2):215-38, ix. doi: 10.1016/j.nic.2011.01.008.
Computed tomographic perfusion (CTP) imaging is an advanced modality that provides important information about capillary-level hemodynamics of the brain parenchyma. CTP can aid in diagnosis, management, and prognosis of acute stroke patients by clarifying acute cerebral physiology and hemodynamic status, including distinguishing severely hypoperfused but potentially salvageable tissue from both tissue likely to be irreversibly infarcted ("core") and hypoperfused but metabolically stable tissue ("benign oligemia"). A qualitative estimate of the presence and degree of ischemia is typically required for guiding clinical management. Radiation dose issues with CTP imaging, a topic of much current concern, are also addressed in this review.
计算机断层灌注（CTP）成像技术是一种先进的手段，可以提供有关脑实质毛细血管水平血液动力学的重要信息。CTP 可以通过阐明急性脑生理学和血液动力学状态，包括区分严重低灌注但可能有救的组织与可能不可逆梗死的组织（“核心”）和低灌注但代谢稳定的组织（“良性低灌注”），来帮助急性脑卒中患者的诊断、治疗和预后。通常需要定性估计缺血的存在和程度，以指导临床管理。本综述还涉及 CTP 成像的辐射剂量问题，这是当前关注的一个热点话题。
