足月配方奶喂养婴儿发生严重获得性巨细胞病毒感染：病例报告。
Severe acquired cytomegalovirus infection in a full-term, formula-fed infant: case report.
机构信息
Unità Operativa di Terapia Intensiva Neonatale, Azienda Ospedaliero-Universitaria Policlinico di Modena, Italy.
出版信息
BMC Pediatr. 2011 Jun 6;11:52. doi: 10.1186/1471-2431-11-52.
Abstract
BACKGROUND
Cases of cytomegalovirus colitis are exceptionally reported in immuno-competent infant. The pathogenesis is uncertain but breast-feeding is considered as a main source of postnatal infection.
CASE PRESENTATION
Here we report a full-term, formula-fed infant who developed a severe cytomegalovirus anaemia and colitis when aged 2 months.
CONCLUSION
Even if the molecular identity between the cytomegalovirus-isolate of the infant and the maternal virus could not be demonstrated, we confirmed through laboratory investigation that cytomegalovirus infection was acquired postnatally. However, the source of cytomegalovirus infection remained unclear. Alternative modes of cytomegalovirus transmission are discussed.
摘要
背景
免疫功能正常的婴儿中极少见巨细胞病毒性结肠炎病例。发病机制尚不确定，但母乳喂养被认为是产后感染的主要来源。
病例介绍
这里我们报告一例 2 月龄、配方奶喂养的足月婴儿，出现严重巨细胞病毒贫血和结肠炎。
结论
即使不能证明婴儿的巨细胞病毒分离株与母体病毒具有分子同一性，我们通过实验室研究证实巨细胞病毒感染是在产后获得的。然而，巨细胞病毒感染的来源仍不清楚。讨论了其他巨细胞病毒传播方式。
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